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Details on Person PTGS2 dimer [endoplasmic reticulum membrane]

Class:Id	Complex:140491
_displayName	PTGS2 dimer [endoplasmic reticulum membrane]
_timestamp	2012-06-06 20:01:10
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:140485] Jassal, B, 2004-08-19 08:33:01
hasComponent	[EntityWithAccessionedSequence:61605] PTGS2 [endoplasmic reticulum membrane] [Homo sapiens] [EntityWithAccessionedSequence:61605] PTGS2 [endoplasmic reticulum membrane] [Homo sapiens] [SimpleEntity:2311355] heme b [endoplasmic reticulum membrane]
literatureReference	[LiteratureReference:2311352] Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer
modified	[InstanceEdit:141703] Jassal, B, 2004-10-01 07:42:23 [InstanceEdit:143526] Schmidt, EE, 2004-11-12 06:42:33 [InstanceEdit:435398] Jupe, S, 2009-09-09 [InstanceEdit:561301] D'Eustachio, P, 2010-04-02 [InstanceEdit:2162166] Williams, MG, 2012-03-14 [InstanceEdit:2311358] D'Eustachio, P, 2012-06-06
name	PTGS2 dimer PGHS2 dimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:365648] R-HSA-140491.1
(hasComponent)	[Complex:2309778] PTGS2 dimer:PTGS2 inhibitors [endoplasmic reticulum membrane] [Homo sapiens] [Complex:9716835] PTGS2 dimer:PTGS inhibitors [endoplasmic reticulum membrane] [Homo sapiens]
(hasMember)	[DefinedSet:428985] PTGS dimers [endoplasmic reticulum membrane] [Homo sapiens]
(input)	[Reaction:2309779] PTGS2 dimer binds PTGS2 inhibitors [Homo sapiens] [Reaction:2314686] ASA- acetylates PTGS2 [Homo sapiens] [Reaction:9716836] PTGS2 dimer binds PTGS inhibitors [Homo sapiens] [Reaction:9716838] PTGS1,2 dimers bind PTGS Inhibitors [Homo sapiens]
(physicalEntity)	[CatalystActivity:2309772] prostaglandin-endoperoxide synthase activity of PTGS2 dimer [endoplasmic reticulum membrane] [CatalystActivity:2309777] peroxidase activity of PTGS2 dimer [endoplasmic reticulum membrane] [CatalystActivity:9026406] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen of PTGS2 dimer [endoplasmic reticulum membrane] [CatalystActivity:9027536] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of PTGS2 dimer [endoplasmic reticulum membrane]
(updatedInstance)	[_UpdateTracker:9868303] Update Tracker - [Complex:140491] PTGS2 dimer [endoplasmic reticulum membrane] - v30:[add_removeCompartment, modifyName] [_UpdateTracker:9869490] Update Tracker - [Complex:140491] PTGS2 dimer [endoplasmic reticulum membrane] - v33:[modifyName] [_UpdateTracker:9872498] Update Tracker - [Complex:140491] PTGS2 dimer [endoplasmic reticulum membrane] - v41:[addName] [_UpdateTracker:9872931] Update Tracker - [Complex:140491] PTGS2 dimer [endoplasmic reticulum membrane] - v42:[addHasComponent, addLiteratureReference]
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No pathways have been reviewed or authored by PTGS2 dimer [endoplasmic reticulum membrane] (140491)