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Details on Person Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
| Class:Id | LiteratureReference:140387 |
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| _displayName | Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis |
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| _timestamp | 2004-08-18 15:49:46 |
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| author | [Person:140388] Oda, E
[Person:140389] Ohki, R
[Person:140390] Murasawa, H
[Person:140391] Nemoto, J
[Person:140392] Shibue, T
[Person:140393] Yamashita, T
[Person:69407] Tokino, T
[Person:110831] Taniguchi, T
[Person:140402] Tanaka, N |
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| created | [InstanceEdit:140377] Gopinathrao, G, 2004-08-18 11:49:08 |
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| journal | Science |
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| pages | 1053-8 |
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| pubMedIdentifier | 10807576 |
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| title | Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis |
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| volume | 288 |
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| year | 2000 |
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| (literatureReference) | [Complex:4331332] p-S15,S20-TP53 Tetramer:PMAIP1 Gene [nucleoplasm] [Homo sapiens]
[Summation:140386] It was observed that cytosolic Noxa underwent BH3 motif-depe...
[Summation:508155] BH3-only proteins (tBid, BIM, PUMA, BAD, NOXA) associate wit...
[Summation:508164] Bcl-2 interacts with tBid (Yi et al. 2003), BIM (Puthalakath...
[Summation:9028950] Bcl-2 interacts with tBid (Yi et al. 2003), BIM (Puthalakath...
[BlackBoxEvent:140214] TP53 stimulates PMAIP1 (NOXA) expression [Homo sapiens]
[Reaction:140216] Translocation of PMAIP1 (NOXA) to mitochondria [Homo sapiens]
[Reaction:140225] Interaction of NOXA and Bcl-2 [Mus musculus]
[Reaction:140228] Interaction of NOXA and Bcl-XL [Mus musculus]
[Reaction:508162] BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL [Homo sapiens] |
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