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Details on Person It was observed that cytosolic Noxa underwent BH3 motif-depe...

Class:IdSummation:140386
_displayNameIt was observed that cytosolic Noxa underwent BH3 motif-depe...
_timestamp2004-08-20 15:39:41
created[InstanceEdit:140377] Gopinathrao, G, 2004-08-18 11:49:08
literatureReference[LiteratureReference:140387] Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
modified[InstanceEdit:140556] Gopinathrao, G, 2004-08-20 15:39:40
textIt was observed that cytosolic Noxa underwent BH3 motif-dependent localization to mitochondria and interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9.
(summation)[Reaction:140216] Translocation of PMAIP1 (NOXA) to mitochondria [Homo sapiens]
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