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Details on Person Arachidonate is oxidised to PGG2 by PTGS1

Class:IdReaction:140355
_displayNameArachidonate is oxidised to PGG2 by PTGS1
_doReleaseTRUE
_timestamp2024-07-11 22:30:40
authored[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
catalystActivity[CatalystActivity:140354] prostaglandin-endoperoxide synthase activity of PTGS1 dimer [endoplasmic reticulum membrane]
catalystActivityReference[CatalystActivityReference:9915553] prostaglandin-endoperoxide synthase activity of PTGS1 dimer [endoplasmic reticulum membrane] Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system
compartment[Compartment:17957] endoplasmic reticulum lumen
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:140352] Jassal, B, 2004-08-13 10:35:27
crossReference[DatabaseIdentifier:9915546] RHEA:42597
edited[InstanceEdit:351780] Jassal, B, 2008-05-28 09:06:10
[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
input[SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
[SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
[SimpleEntity:140356] AA [endoplasmic reticulum lumen]
literatureReference[LiteratureReference:140560] Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation
[LiteratureReference:140564] Isolation and properties of intermediates in prostaglandin biosynthesis
modified[InstanceEdit:140558] Jassal, B, 2004-08-23 05:31:01
[InstanceEdit:141702] Jassal, B, 2004-09-30 09:25:15
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:266179] Jassal, B, 2008-04-25 13:27:59
[InstanceEdit:350189] Jassal, B, 2008-05-14 09:43:11
[InstanceEdit:350226] Jassal, B, 2008-05-15 08:18:31
[InstanceEdit:350661] Jassal, Bijay, 2008-05-20
[InstanceEdit:350840] Jassal, B, 2008-05-21 10:32:15
[InstanceEdit:351780] Jassal, B, 2008-05-28 09:06:10
[InstanceEdit:352324] Jassal, B, 2008-06-02 12:56:30
[InstanceEdit:352333] Jassal, B, 2008-06-02 13:27:43
[InstanceEdit:380824] Jassal, Bijay, 2008-11-17
[InstanceEdit:443839] Jupe, S, 2009-10-12
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:2162165] Williams, MG, 2012-03-14
[InstanceEdit:2309789] D'Eustachio, P, 2012-06-05
[InstanceEdit:2569041] D'Eustachio, P, 2012-11-10
[InstanceEdit:2586591] D'Eustachio, P, 2012-11-15
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9915565] D'Eustachio, Peter, 2024-07-11
nameArachidonate is oxidised to PGG2 by PTGS1
(5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 => prostaglandin G2
Arachidonate oxidised to PGG2
output[SimpleEntity:140357] PGG2 [endoplasmic reticulum lumen]
precedingEvent
releaseDate2008-06-30
reviewed[InstanceEdit:2569042] Rush, MG, 2012-11-10
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359863] R-HSA-140355.3
summation[Summation:178473] Prostaglandin G/H synthase PTGS1 exhibits a dual catalytic a...
(hasEvent)[Pathway:140180] COX reactions [Homo sapiens]
[Pathway:2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) [Homo sapiens]
(precedingEvent)[Reaction:140359] PGG2 is reduced to PGH2 by PTGS1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9788382] Update Tracker - [Reaction:140355] Arachidonic acid is oxidised to PGG2 by PTGS1 - v42:[modifyText]
[_UpdateTracker:9788513] Update Tracker - [Reaction:140355] Arachidonic acid is oxidised to PGG2 by PTGS1 - v41:[modifyText]
[_UpdateTracker:9791856] Update Tracker - [Reaction:140355] Arachidonic acid is oxidised to PGG2 by PTGS1 - v25:[modifyText]
[_UpdateTracker:9919373] Update Tracker - [Reaction:140355] Arachidonate is oxidised to PGG2 by PTGS1 - v90:[modifyText]
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