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Details on Person Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets

Class:Id	LiteratureReference:140093
_displayName	Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets
_timestamp	2004-08-12 09:56:57
author	[Person:140049] Banno, Y [Person:140094] Yada, Y [Person:140095] Nozawa, Y
created	[InstanceEdit:139985] de Bono, B, 2004-08-12 05:56:15
journal	J Biol Chem
pages	11459-65
pubMedIdentifier	2841328
title	Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets
volume	263
year	1988
(literatureReference)	[Reaction:114688] PLC-beta hydrolyses PIP2 to DAG and IP3 [Homo sapiens] [Reaction:114689] PLC gamma 2-mediated PIP2 hydrolysis [Homo sapiens] [Reaction:398193] PLC beta-mediated PIP2 hydrolysis [Homo sapiens] [Reaction:399998] Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate [Homo sapiens] [Reaction:1855221] PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane [Homo sapiens] [Reaction:8983503] PLC-beta:G-alpha(q/11):DAG:IP3 dissociates to give DAG and IP3 [Homo sapiens] [Reaction:8983510] PLC-beta:G-alpha(q/11) binds PIP2 [Homo sapiens]
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