Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Sequestration of BAD protein by 14-3-3

Class:Id	Reaction:139899
_displayName	Sequestration of BAD protein by 14-3-3
_doRelease	TRUE
_timestamp	2016-11-10 00:57:17
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:139911] Hardwick, JM, Tsujimoto, Y, 2004-08-09 19:10:09
input	[EntityWithAccessionedSequence:198335] p-S99-BAD [cytosol] [Homo sapiens] [DefinedSet:1445138] 14-3-3 dimer [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:3139020] 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation [LiteratureReference:140433] Cleavage of 14-3-3 protein by caspase-3 facilitates bad interaction with Bcl-x(L) during apoptosis [LiteratureReference:3143411] Functional conservation of 14-3-3 isoforms in inhibiting bad-induced apoptosis [LiteratureReference:3143412] Association of 14-3-3gamma and phosphorylated bad attenuates injury in ischemic astrocytes
modified	[InstanceEdit:139947] Gopinathrao, G, 2004-08-10 16:19:27 [InstanceEdit:140201] Gopinathrao, G, 2004-08-12 15:53:46 [InstanceEdit:140377] Gopinathrao, G, 2004-08-18 11:49:08 [InstanceEdit:141115] Gopinathrao, G, 2004-08-31 17:54:38 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:170871] D'Eustachio, P, 2006-01-18 15:25:09 [InstanceEdit:3139023] Orlic-Milacic, M, 2013-02-13 [InstanceEdit:3142705] Orlic-Milacic, M, 2013-02-13 [InstanceEdit:3142706] Orlic-Milacic, M, 2013-02-13 [InstanceEdit:3143413] Orlic-Milacic, M, 2013-02-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Sequestration of BAD protein by 14-3-3
output	[Complex:139904] 14-3-3 proteins:p-S99-BAD complex [cytosol] [Homo sapiens]
precedingEvent	[Reaction:198347] AKT phosphorylates BAD [Homo sapiens] [Reaction:198270] PDPK1 phosphorylates AKT at T308 [Homo sapiens]
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:3139052] Orlic-Milacic, M, 2013-02-13
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360677] R-HSA-139899.3
summation	[Summation:179175] 14-3-3 proteins bind BAD phosphorylated by activated AKT on ...
(hasEvent)	[Pathway:111447] Activation of BAD and translocation to mitochondria [Homo sapiens]
(precedingEvent)	[Reaction:139906] Activation of BAD by calcineurin [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787909] Update Tracker - [Reaction:139899] Sequestration of BAD protein by 14-3-3 - v44:[addLiteratureReference, add_removeInput, modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by Sequestration of BAD protein by 14-3-3 (139899)