Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Caspase-8 activates BID by cleavage

Class:Id	Reaction:139898
_displayName	Caspase-8 activates BID by cleavage
_doRelease	TRUE
_timestamp	2016-11-10 00:57:05
authored	[InstanceEdit:163352] Gopinathrao, G, 2005-04-27 18:07:06
catalystActivity	[CatalystActivity:139951] cysteine-type endopeptidase activity of active caspase-8 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:139894] Gopinathrao, G, 2004-08-09 18:50:00
figure	[Figure:140540] /figures/bid1.jpg
input	[EntityWithAccessionedSequence:50825] BID(1-195) [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:140419] Caspase 8-mediated cleavage of the pro-apoptotic BCL-2 family member BID in p53-dependent apoptosis
modified	[InstanceEdit:139947] Gopinathrao, G, 2004-08-10 16:19:27 [InstanceEdit:140201] Gopinathrao, G, 2004-08-12 15:53:46 [InstanceEdit:140377] Gopinathrao, G, 2004-08-18 11:49:08 [InstanceEdit:141302] Gopinathrao, G, 2004-09-14 11:08:02 [InstanceEdit:141727] Gopinathrao, G, 2004-10-01 18:23:59 [InstanceEdit:163352] Gopinathrao, G, 2005-04-27 18:07:06 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2534322] Matthews, L, 2012-10-24 [InstanceEdit:8861950] Orlic-Milacic, Marija, 2016-02-22 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Caspase-8 activates BID by cleavage
output	[EntityWithAccessionedSequence:139953] BID(61-195) [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:139952] Caspase-8 processing in the DISC [Homo sapiens] [Reaction:141156] TRAIL-mediated dimerization of procaspase-8 [Homo sapiens] [Reaction:141159] TNF-mediated dimerization of procaspase-8 [Homo sapiens] [Reaction:73945] FAS-mediated dimerization of procaspase-8 [Homo sapiens] [BlackBoxEvent:6791291] TP53 stimulates BID gene expression [Homo sapiens] [Reaction:6791285] TP53 binds the BID gene promoter [Homo sapiens]
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359937] R-HSA-139898.4
summation	[Summation:163355] The caspase 8 -mediated cleavage of cytosolic, inactive p22 ...
(hasEvent)	[Pathway:75108] Activation, myristolyation of BID and translocation to mitochondria [Homo sapiens]
(precedingEvent)	[Reaction:141367] Myristoylation of tBID by NMT1 [Homo sapiens] [Reaction:168849] tBID binds to inactive BAX protein [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Caspase-8 activates BID by cleavage (139898)