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Details on Person Expression of NAMPT (NamPRT, PBEF, Visfatin)

Class:Id	BlackBoxEvent:1368889
_displayName	Expression of NAMPT (NamPRT, PBEF, Visfatin)
_doRelease	TRUE
_timestamp	2025-03-06 22:55:38
authored	[InstanceEdit:1368177] May, B, 2011-06-29
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:1368921] May, B, 2011-06-30
edited	[InstanceEdit:1368177] May, B, 2011-06-29
inferredFrom	[BlackBoxEvent:1368914] Expression of Nampt [Mus musculus]
input	[EntityWithAccessionedSequence:5641210] NAMPT gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1368898] Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes
modified	[InstanceEdit:1799319] May, B, 2011-10-23 [InstanceEdit:5641233] May, Bruce, 2014-11-16 [InstanceEdit:5663195] May, Bruce, 2015-01-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626999] May, Bruce, 2018-10-31 [InstanceEdit:9697139] May, Bruce, 2020-08-06 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9940986] May, Bruce, 2025-03-06
name	Expression of NAMPT (NamPRT, PBEF, Visfatin)
output	[EntityWithAccessionedSequence:197188] NAMPT [cytosol] [Homo sapiens]
precedingEvent	[Reaction:5663122] p-S90-BMAL1:p-T451,T461-CLOCK binds NAMPT gene [Homo sapiens] [BlackBoxEvent:9920665] p-S90-BMAL1:p-T451,T461-CLOCK translocates from the cytosol to the nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:1368960] Positive gene expression regulation by 'p-S90-BMAL1:p-T451,T461-CLOCK:NAMPT gene [nucleoplasm]'
releaseDate	2011-12-06
reviewed	[InstanceEdit:879756] Albrecht, Urs, 2010-06-23 [InstanceEdit:879786] Delaunay, F, 2010-06-23 [InstanceEdit:879790] Hirota, T, 2010-06-23 [InstanceEdit:879726] Kay, SA, 2010-06-23 [InstanceEdit:9940981] Albrecht, Urs, 2025-03-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016512] R-HSA-1368889.7
summation	[Summation:1368876] The NAMPT (NamPRT) gene is transcribed to yield mRNA and the... [Summation:1368963] As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) hetero...
(hasEvent)	[Pathway:1368108] BMAL1:CLOCK,NPAS2 activates circadian expression [Homo sapiens]
(precedingEvent)	[Reaction:197250] NAMPT transfers PRIB to NAM to form NAMN [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776037] Update Tracker - [BlackBoxEvent:1368889] Expression of NAMPT (NamPRT, PBEF, Visfatin) - v78:[addSummation] [_UpdateTracker:9785262] Update Tracker - [BlackBoxEvent:1368889] Expression of NAMPT (NamPRT, PBEF, Visfatin) - v52:[add_removeRegulator] [_UpdateTracker:9785649] Update Tracker - [BlackBoxEvent:1368889] Expression of NAMPT (NamPRT, PBEF, Visfatin) - v51:[addInput] [_UpdateTracker:9787157] Update Tracker - [BlackBoxEvent:1368889] Expression of NAMPT (NamPRT, PBEF, Visfatin) - v46:[modifyText]
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No pathways have been reviewed or authored by Expression of NAMPT (NamPRT, PBEF, Visfatin) (1368889)