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Details on Person DREAM complex [nucleoplasm]

Class:Id	Complex:1362264
_displayName	DREAM complex [nucleoplasm]
_timestamp	2017-02-17 13:07:22
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1362263] Orlic-Milacic, Marija, 2011-06-07
hasComponent	[Complex:1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:389102] RBL2 [nucleoplasm] [Homo sapiens] [DefinedSet:1226069] E2F4,E2F5 [nucleoplasm] [Homo sapiens] [DefinedSet:1362227] TFDP1,TFDP2 [nucleoplasm] [Homo sapiens] [Complex:1362259] p-MuvB complex [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:389101] LIN37 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:389103] LIN54 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:389108] LIN9 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:1362251] p-S28-LIN52 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:212223] RBBP4 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1362256] Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
modified	[InstanceEdit:8964461] Orlic-Milacic, Marija, 2017-02-17
name	DREAM complex
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591642] R-HSA-1362264.2
(activeUnit)	[NegativeGeneExpressionRegulation:8964503] Negative gene expression regulation by 'DREAM complex:CDC25A gene [nucleoplasm]' [NegativeGeneExpressionRegulation:8964507] Negative gene expression regulation by 'DREAM complex:CDC6 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:8964514] Negative gene expression regulation by 'DREAM complex:E2F1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:8964518] Negative gene expression regulation by 'DREAM complex:PCNA gene [nucleoplasm]' [NegativeGeneExpressionRegulation:8964523] Negative gene expression regulation by 'DREAM complex:RBL1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:8964532] Negative gene expression regulation by 'DREAM complex:TOP2A gene [nucleoplasm]'
(hasComponent)	[Complex:8964464] DREAM complex:PCNA gene [nucleoplasm] [Homo sapiens] [Complex:8964470] DREAM complex:CDC25A gene [nucleoplasm] [Homo sapiens] [Complex:8964478] DREAM complex:TOP2A gene [nucleoplasm] [Homo sapiens] [Complex:8964483] DREAM complex:E2F1 gene [nucleoplasm] [Homo sapiens] [Complex:8964487] DREAM complex:RBL1 gene [nucleoplasm] [Homo sapiens] [Complex:8964499] DREAM complex:CDC6 gene [nucleoplasm] [Homo sapiens]
(input)	[Reaction:8964465] DREAM complex binds the PCNA gene promoter [Homo sapiens] [Reaction:8964471] DREAM complex binds the CDC25A gene promoter [Homo sapiens] [Reaction:8964475] DREAM complex binds the TOP2A gene promoter [Homo sapiens] [Reaction:8964482] DREAM complex binds the E2F1 gene promoter [Homo sapiens] [Reaction:8964492] DREAM complex binds the RBL1 gene promoter [Homo sapiens] [Reaction:8964498] DREAM complex binds the CDC6 gene promoter [Homo sapiens]
(output)	[Reaction:1362261] p130 (RBL2) associates with MuvB to form DREAM complex [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9888669] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v47:[updateContainedComponent] [_UpdateTracker:9894144] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v56:[updateContainedComponent] [_UpdateTracker:9896356] Update Tracker - [Complex:1362264] DREAM complex [nucleoplasm] - v60:[addLiteratureReference]
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No pathways have been reviewed or authored by DREAM complex [nucleoplasm] (1362264)