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Details on Person p130 (RBL2) associates with MuvB to form DREAM complex

Class:Id	Reaction:1362261
_displayName	p130 (RBL2) associates with MuvB to form DREAM complex
_doRelease	TRUE
_timestamp	2011-09-09 09:07:37
authored	[InstanceEdit:1363332] Orlic-Milacic, Marija, 2011-06-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1362263] Orlic-Milacic, Marija, 2011-06-07
input	[Complex:1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] [Homo sapiens] [Complex:1362259] p-MuvB complex [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1362256] Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence [LiteratureReference:1362262] DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly
modified	[InstanceEdit:1363600] Orlic-Milacic, Marija, 2011-06-15 [InstanceEdit:1493105] Orlic-Milacic, Marija, 2011-08-15 [InstanceEdit:1538149] Orlic-Milacic, Marija, 2011-08-26 [InstanceEdit:1538173] Orlic-Milacic, Marija, 2011-08-26 [InstanceEdit:1579360] Orlic-Milacic, Marija, 2011-09-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p130 (RBL2) associates with MuvB to form DREAM complex
output	[Complex:1362264] DREAM complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:1362270] Phosphorylation of LIN52 component of MuvB by DYRK1A [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1538129] MacPherson, D, 2011-08-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591452] R-HSA-1362261.2
summation	[Summation:1362257] In G0 and early G1, p130 (RBL2) bound to E2F4 or E2F5 and DP...
(hasEvent)	[Pathway:1538133] G0 and Early G1 [Homo sapiens]
(precedingEvent)	[Pathway:1362277] Transcription of E2F targets under negative control by DREAM complex [Homo sapiens] [Reaction:8964465] DREAM complex binds the PCNA gene promoter [Homo sapiens] [Reaction:8964471] DREAM complex binds the CDC25A gene promoter [Homo sapiens] [Reaction:8964475] DREAM complex binds the TOP2A gene promoter [Homo sapiens] [Reaction:8964482] DREAM complex binds the E2F1 gene promoter [Homo sapiens] [Reaction:8964492] DREAM complex binds the RBL1 gene promoter [Homo sapiens] [Reaction:8964498] DREAM complex binds the CDC6 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by p130 (RBL2) associates with MuvB to form DREAM complex (1362261)