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Details on Person Self-ubiquitination of RNF41

Class:IdReaction:1358789
_displayNameSelf-ubiquitination of RNF41
_doReleaseTRUE
_timestamp2024-03-20 23:47:16
authored[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04
catalystActivity[CatalystActivity:1358794] ubiquitin-protein transferase activity of RNF41 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:1358799] Orlic-Milacic, Marija, 2011-06-02
edited[InstanceEdit:1972361] Matthews, L, 2011-11-07
input[EntityWithAccessionedSequence:975977] RNF41 [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:1358726] Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
modified[InstanceEdit:1474296] Orlic-Milacic, Marija, 2011-08-05
[InstanceEdit:1972362] Orlic-Milacic, M, 2011-11-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9866055] Orlic-Milacic, Marija, 2024-03-20
nameSelf-ubiquitination of RNF41
negativePrecedingEvent[NegativePrecedingEvent:9866048] Futile Cycle: Deubiquitination of RNF41 by P-USP8
[NegativePrecedingEvent:9866022] Futile Cycle: RNF41 ubiquitinates ERBB3
[NegativePrecedingEvent:9866035] Futile Cycle: RNF41 ubiquitinates activated ERBB3
output[Complex:1358737] Ub-RNF41 [cytosol] [Homo sapiens]
releaseDate2011-12-06
reviewed[InstanceEdit:1972347] Neckers, LM, 2011-11-11
[InstanceEdit:1972346] Xu, W, 2011-11-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016529] R-HSA-1358789.3
summation[Summation:1358770] RNF41 is able to self-ubiquitinate, which keeps its levels l...
(hasEvent)[Pathway:1358803] Downregulation of ERBB2:ERBB3 signaling [Homo sapiens]
(precedingEvent)[Reaction:1358797] Ubiquitinated RNF41 binds P-USP8 [Homo sapiens]
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No pathways have been reviewed or authored by Self-ubiquitination of RNF41 (1358789)