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Details on Person Orlic-Milacic, Marija, 2011-06-02

Class:Id	InstanceEdit:1358723
_displayName	Orlic-Milacic, Marija, 2011-06-02
_timestamp	2011-06-02 15:19:24
author	[Person:1169272] Orlic-Milacic, Marija
dateTime	2011-06-02 19:19:24
(created)	[LiteratureReference:1358720] ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor [LiteratureReference:1358721] Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells [LiteratureReference:1358722] Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8 [LiteratureReference:1358724] Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1 [LiteratureReference:1358725] Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2 [LiteratureReference:1358726] Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3 [LiteratureReference:1358727] Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects [LiteratureReference:1358728] Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2011-06-02 (1358723)