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Details on Person ERBIN [plasma membrane]
Class:Id EntityWithAccessionedSequence:1358718
_displayName ERBIN [plasma membrane]
_timestamp 2019-05-24 16:18:45
compartment [Compartment:876] plasma membrane
created [InstanceEdit:1358717] Orlic-Milacic, Marija, 2011-06-02
endCoordinate 1412
modified [InstanceEdit:9646486] Orlic-Milacic, Marija, 2019-05-24
name ERBIN ERBB2IP LAP2
referenceEntity [ReferenceGeneProduct:149547] UniProt:Q96RT1 ERBIN [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:2017425] R-HSA-1358718.2
startCoordinate 1
(hasCandidate) [CandidateSet:9013003] RHOA plasma membrane effectors [cytosol] [Homo sapiens] [CandidateSet:9013052] RHOB effectors (plasma membrane) [cytosol] [Homo sapiens] [CandidateSet:9013138] RHOC effectors [cytosol] [Homo sapiens] [CandidateSet:9013178] RAC1 effectors [cytosol] [Homo sapiens] [CandidateSet:9014425] RAC2 plasma membrane effectors [cytosol] [Homo sapiens] [CandidateSet:9014451] RHOG plasma membrane effectors [cytosol] [Homo sapiens] [CandidateSet:9020391] RAC3 effectors [cytosol] [Homo sapiens]
(hasComponent) [Complex:1227970] ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:1918081] Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:1918083] Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9646482] ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9652349] ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9652374] ERBB2 V777L,(ERBB2 V777M,ERBB2 V777E):ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9652375] ERBB2 D769H,(ERBB2 D769Y,ERBB2 D769N):ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9652379] ERBB2 L869R,(ERBB2 L869Q):ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9652380] ERBB2 G778_P780dup:ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens] [Complex:9652381] ERBB2 I767M:ERBIN:HSP90:CDC37 [plasma membrane] [Homo sapiens]
(input) [Reaction:1227971] Association of mature ERBB2 with HSP90 chaperone and its co-chaperone CDC37 [Homo sapiens]
(output) [Reaction:1227964] ERBB2 homodimerization [Homo sapiens] [Reaction:1247500] ERBB2 forms a heterodimer with activated ERBB3 [Homo sapiens] [Reaction:1250227] ERBB2 forms heterodimers with activated ERBB4 isoforms [Homo sapiens] [Reaction:1358796] ERBB2 forms a heterodimer with activated EGFR [Homo sapiens] [Reaction:1963589] ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 [Homo sapiens] [Reaction:9664567] ERBB2 KD mutants heterodimerize [Homo sapiens] [Reaction:9665388] ERBB2 ECD mutants heterodimerize with EGFR [Homo sapiens] [Reaction:9665697] ERBB2 TMD/JMD mutants hetrodimerize [Homo sapiens]
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Pathways
No pathways have been reviewed or authored by ERBIN [plasma membrane] (1358718)