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Details on Person inward rectifier potassium channel activity

Class:Id	GO_MolecularFunction:13181
_displayName	inward rectifier potassium channel activity
_timestamp	2009-11-21 18:36:34
accession	0005242
definition	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
modified	[InstanceEdit:160533] Schmidt, EE, 2005-03-23 05:24:35 [InstanceEdit:162607] Schmidt, EE, 2005-04-01 11:06:09 [InstanceEdit:171322] Schmidt, EE, 2006-02-06 10:50:16 [InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20 [InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39 [InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04 [InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44 [InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57 [InstanceEdit:422569] Kanapin, EE [InstanceEdit:436347] Kanapin, EE [InstanceEdit:447572] Kanapin, EE [InstanceEdit:526073] Kanapin, AA [InstanceEdit:528085] Kanapin, AA [InstanceEdit:615500] Kanapin, AA [InstanceEdit:797782] Kanapin, AA [InstanceEdit:937668] Yung, CK [InstanceEdit:1042299] Yung, CK [InstanceEdit:1220942] Yung, CK [InstanceEdit:1301009] Yung, CK [InstanceEdit:1301023] Yung, CK [InstanceEdit:1552540] Yung, CK [InstanceEdit:1996004] Yung, CK [InstanceEdit:2132408] Weiser, JD [InstanceEdit:2133145] Weiser, JD [InstanceEdit:2266118] Weiser, JD [InstanceEdit:2266147] Weiser, JD [InstanceEdit:2454362] Weiser, JD [InstanceEdit:2455542] Weiser, JD [InstanceEdit:2587907] Weiser, JD [InstanceEdit:3132285] Weiser, JD [InstanceEdit:3445953] Weiser, JD [InstanceEdit:4341211] Weiser, JD [InstanceEdit:5083267] Weiser, JD [InstanceEdit:5263134] Weiser, JD [InstanceEdit:6791824] Weiser, JD [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17
name	inward rectifier potassium channel activity
referenceDatabase	[ReferenceDatabase:1] GO
(activity)	[NegativeRegulation:9729871] Negative regulation by 'H+ [cytosol]' [CatalystActivity:975354] inward rectifier potassium channel activity of Kir heterotetramers [plasma membrane] [CatalystActivity:1299202] inward rectifier potassium channel activity of KCNJ tetramer [plasma membrane] [CatalystActivity:1299208] inward rectifier potassium channel activity of Potassium transport channels (Kir 1.1 and Kir 4.1/5.1) [plasma membrane] [CatalystActivity:1368988] inward rectifier potassium channel activity of ATP sensitive K+ channels-inwardly rectifying (SUR2) [plasma membrane] [CatalystActivity:5678258] inward rectifier potassium channel activity of KCNJ11:ABCC9 [plasma membrane] [CatalystActivity:9631954] inward rectifier potassium channel activity of ABCC9 mutants:KCNJ11 [plasma membrane] [CatalystActivity:9729874] inward rectifier potassium channel activity of KCNJ2 [plasma membrane] [CatalystActivity:9729875] inward rectifier potassium channel activity of Kcnj2 [plasma membrane] [CatalystActivity:9730517] inward rectifier potassium channel activity of O-glycosyl 3a tetramer [plasma membrane] List all 11 refering instances
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No pathways have been reviewed or authored by inward rectifier potassium channel activity (13181)