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Details on Person TIMM22 inserts proteins into inner membrane

Class:Id	Reaction:1307803
_displayName	TIMM22 inserts proteins into inner membrane
_doRelease	TRUE
_timestamp	2023-11-06 06:33:36
authored	[InstanceEdit:1299488] May, B, 2011-05-23
catalystActivity	[CatalystActivity:1307806] membrane insertase activity of TIMM22 [mitochondrial inner membrane]
compartment	[Compartment:17927] mitochondrial intermembrane space [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:1307804] May, B, 2011-05-29
edited	[InstanceEdit:1299488] May, B, 2011-05-23
inferredFrom	[Reaction:1252258] TIM22 complex inserts proteins into inner membrane [Saccharomyces cerevisiae]
input	[CandidateSet:1307796] Cargo of TIMM22 [mitochondrial intermembrane space] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1307738] Multiple pathways for mitochondrial protein traffic [LiteratureReference:1307739] Multiple pathways for sorting mitochondrial precursor proteins
modified	[InstanceEdit:1307807] May, B, 2011-05-29 [InstanceEdit:1955370] May, B, 2011-11-03 [InstanceEdit:1977303] May, B, 2011-11-08 [InstanceEdit:2010553] May, B, 2011-11-22 [InstanceEdit:2108992] May, B, 2012-02-12 [InstanceEdit:2143820] May, B, 2012-02-26 [InstanceEdit:5257491] May, B, 2014-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9852705] May, Bruce, 2023-11-06
name	TIMM22 inserts proteins into inner membrane
output	[CandidateSet:1307800] Cargo of TIMM22 [mitochondrial inner membrane] [Homo sapiens]
precedingEvent	[Reaction:1268022] TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space [Homo sapiens] [Reaction:1299484] TIMM8:TIMM13 chaperones hydrophobic proteins [Homo sapiens] [Reaction:1268022] TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space [Homo sapiens] [Reaction:1955380] TIMM9:TIMM10 transfers proteins to TIMM22 [Homo sapiens] [Reaction:1299481] TIMM9:TIMM10 binds hydrophobic proteins [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:1914221] D'Eustachio, P, 2011-11-01 [InstanceEdit:2108993] Endo, T, 2012-02-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158250] R-HSA-1307803.3
summation	[Summation:1307721] As inferred from the yeast TIM22 complex, human TIMM22 inser...
(hasEvent)	[Pathway:1268020] Mitochondrial protein import [Homo sapiens]
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No pathways have been reviewed or authored by TIMM22 inserts proteins into inner membrane (1307803)