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Query author contributions in Reactome

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Details on Person EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane]

Class:IdComplex:1306958
_displayNameEGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane]
_timestamp2012-04-27 18:27:05
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1306964] Orlic-Milacic, Marija, 2011-05-27
hasComponent
isChimericFALSE
modified[InstanceEdit:1474193] Orlic-Milacic, Marija, 2011-08-05
[InstanceEdit:1963596] Orlic-Milacic, M, 2011-11-03
[InstanceEdit:2000338] Orlic-Milacic, M, 2011-11-21
[InstanceEdit:2213009] Matthews, L, 2012-04-27
nameEGF:p-EGFR:p-ERBB2:GRB2:GAB1
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2017722] R-HSA-1306958.1
(hasComponent)[Complex:1306962] EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] [Homo sapiens]
(input)[Reaction:1306965] Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:9655361] gain_of_function of Phosphorylated EGF:EGFR:ERBB2 L755S,(ERBB2 L755M,ERBB2 L755W) heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655384] gain_of_function of Phosphorylated ERBB2 L755P:EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655438] gain_of_function of Phosphorylated ERBB2 T798I,ERBB2 T798M,(ERBB2 T733I):EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655439] gain_of_function of Phosphorylated ERBB2 T862A:EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655441] gain_of_function of Phosphorylated ERBB2 V777L,(ERBB2 V777M,ERBB2 V777E):EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655442] gain_of_function of Phosphorylated ERBB2 H878Y,(ERBB2 H878R):EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655443] gain_of_function of Phosphorylated ERBB2:I767M:EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9655446] gain_of_function of Phosphorylated ERBB2 P780_Y781insGSP:EGFR heterodimer:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9664931] gain_of_function of p-6Y-ERBB2 KD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
[EntityFunctionalStatus:9665451] gain_of_function of p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
(output)[Reaction:1306963] Binding of GRB2:GAB1 to p-ERBB2:p-EGFR [Homo sapiens]
(updatedInstance)[_UpdateTracker:9872197] Update Tracker - [Complex:1306958] EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] - v41:[removeCompartment, updateContainedComponent]
[_UpdateTracker:9873062] Update Tracker - [Complex:1306958] EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] - v42:[updateContainedComponent]
[_UpdateTracker:9877271] Update Tracker - [Complex:1306958] EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] - v44:[updateContainedComponent]
[_UpdateTracker:9894691] Update Tracker - [Complex:1306958] EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] - v57:[updateContainedComponent]
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No pathways have been reviewed or authored by EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (1306958)
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