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Details on Person cell surface receptor signaling pathway via JAK-STAT

Class:IdGO_BiologicalProcess:13033
_displayNamecell surface receptor signaling pathway via JAK-STAT
_timestamp2024-05-14 19:09:10
accession0007259
definitionA cell surface receptor signaling pathway in which ligand binding causes the receptor to dimerize, bringing the receptor-associated JAKs into close proximity. The JAKs then phosphorylate and activate each other on tyrosine residues.This leads to the activation of associated STAT protein, causing the STATs to dissociate from the receptor, translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
modified[InstanceEdit:160533] Schmidt, EE, 2005-03-23 05:24:35
[InstanceEdit:162607] Schmidt, EE, 2005-04-01 11:06:09
[InstanceEdit:171322] Schmidt, EE, 2006-02-06 10:50:16
[InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20
[InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39
[InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04
[InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44
[InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57
[InstanceEdit:422569] Kanapin, EE
[InstanceEdit:436347] Kanapin, EE
[InstanceEdit:447572] Kanapin, EE
[InstanceEdit:526073] Kanapin, AA
[InstanceEdit:528085] Kanapin, AA
[InstanceEdit:615500] Kanapin, AA
[InstanceEdit:797782] Kanapin, AA
[InstanceEdit:937668] Yung, CK
[InstanceEdit:1042299] Yung, CK
[InstanceEdit:1220942] Yung, CK
[InstanceEdit:1301009] Yung, CK
[InstanceEdit:1301023] Yung, CK
[InstanceEdit:1552540] Yung, CK
[InstanceEdit:1996004] Yung, CK
[InstanceEdit:2132408] Weiser, JD
[InstanceEdit:2133145] Weiser, JD
[InstanceEdit:2266118] Weiser, JD
[InstanceEdit:2266147] Weiser, JD
[InstanceEdit:2454362] Weiser, JD
[InstanceEdit:2455542] Weiser, JD
[InstanceEdit:2587907] Weiser, JD
[InstanceEdit:3132285] Weiser, JD
[InstanceEdit:3445953] Weiser, JD
[InstanceEdit:4341211] Weiser, JD
[InstanceEdit:5083267] Weiser, JD
[InstanceEdit:5263134] Weiser, JD
[InstanceEdit:9637466] Weiser, JD
[InstanceEdit:9637561] Weiser, JD
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
namecell surface receptor signaling pathway via JAK-STAT
referenceDatabase[ReferenceDatabase:1] GO
(goBiologicalProcess)[Pathway:209405] JAK/STAT pathway [Drosophila melanogaster]
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