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Details on Person UniProt:Q8JJC0 ZIC1
| Class:Id | ReferenceGeneProduct:1300843 |
|---|---|
| _chainChangeLog | chain:1-444 added on Fri February 6 2015 |
| _displayName | UniProt:Q8JJC0 ZIC1 |
| _timestamp | 2023-11-03 15:54:16 |
| chain | chain:1-444 |
| checksum | D5091DF5796D7F5B |
| comment | FUNCTION Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).SUBCELLULAR LOCATION Expressed in dorsal undifferentiated neural cells in the spinal cord at stages 8 and 23 (at protein level). Expressed in the dorsal neural tube along almost the entire rostrocaudal extent and dorsomedial somites at stage 8. Expressed in the dorsal hindbrain, spinal cord, midbrain and forebrain at stage 17. Expressed in somites and the dorsal CNS at stage 23.SIMILARITY Belongs to the GLI C2H2-type zinc-finger protein family. |
| created | [InstanceEdit:1300696] Yung, CK |
| description | recommendedName: Zinc finger protein ZIC 1 alternativeName: Zinc finger protein of the cerebellum 1 |
| geneName | ZIC1 ZIC |
| identifier | Q8JJC0 |
| isSequenceChanged | FALSE |
| keyword | Activator Cytoplasm Developmental protein Differentiation DNA-binding Metal-binding Neurogenesis Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger |
| modified | [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | ZIC1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | ZIC1_CHICK |
| sequenceLength | 444 |
| species | [Species:49591] Gallus gallus |
| (referenceEntity) | [EntityWithAccessionedSequence:9835292] ZIC1 [nucleoplasm] [Gallus gallus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q8JJC0 ZIC1 (1300843)
