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Details on Person MPP cleaves targeting peptide (presequence) of inner membrane precursors

Class:IdReaction:1299476
_displayNameMPP cleaves targeting peptide (presequence) of inner membrane precursors
_doReleaseTRUE
_timestamp2023-11-06 06:24:41
authored[InstanceEdit:1299477] May, B, 2011-05-21
catalystActivity[CatalystActivity:1299486] metalloendopeptidase activity of Mitochondrial processing peptidase [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
[Compartment:70616] mitochondrial inner membrane
created[InstanceEdit:1299483] May, B, 2011-05-23
edited[InstanceEdit:1299477] May, B, 2011-05-21
inferredFrom
input[SimpleEntity:113521] H2O [mitochondrial matrix]
[Complex:1299473] TIMM23 SORT:Precursor Cargo [mitochondrial inner membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:1307738] Multiple pathways for mitochondrial protein traffic
[LiteratureReference:1307739] Multiple pathways for sorting mitochondrial precursor proteins
modified[InstanceEdit:1299488] May, B, 2011-05-23
[InstanceEdit:1307804] May, B, 2011-05-29
[InstanceEdit:1977303] May, B, 2011-11-08
[InstanceEdit:2010553] May, B, 2011-11-22
[InstanceEdit:2108992] May, B, 2012-02-12
[InstanceEdit:2143820] May, B, 2012-02-26
[InstanceEdit:5257491] May, B, 2014-02-06
[InstanceEdit:8956354] May, Bruce, 2017-01-22
[InstanceEdit:8986208] May, Bruce, 2017-04-22
[InstanceEdit:9024929] May, Bruce, 2017-10-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9852701] May, Bruce, 2023-11-06
nameMPP cleaves targeting peptide (presequence) of inner membrane precursors
output[CandidateSet:8986177] Mitochondrial targeting peptides (from inner membrane proteins) [mitochondrial matrix] [Homo sapiens]
[Complex:1299469] TIMM23 SORT:Cargo [mitochondrial inner membrane] [Homo sapiens]
precedingEvent
releaseDate2012-03-13
reviewed[InstanceEdit:1914221] D'Eustachio, P, 2011-11-01
[InstanceEdit:2108993] Endo, T, 2012-02-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2158243] R-HSA-1299476.6
summation[Summation:1307723] As inferred from yeast, the alpha subunit of the mitochondri...
(hasEvent)[Pathway:1268020] Mitochondrial protein import [Homo sapiens]
(precedingEvent)[Reaction:1299482] TIMM23 SORT inserts proteins into inner membrane [Homo sapiens]
[BlackBoxEvent:8986181] PITRM1 proteolyzes mitochondrial targeting peptides (presequences) [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780235] Update Tracker - [Reaction:1299476] MPP cleaves targeting peptide (presequence) of inner membrane precursors - v63:[addInput]
[_UpdateTracker:9781220] Update Tracker - [Reaction:1299476] MPP cleaves targeting peptide (presequence) of inner membrane precursors - v61:[addOutput]
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