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Details on Person Increase in intracellular concentration of Ca2+ ions and mem...
| Class:Id | Summation:1299225 |
|---|---|
| _displayName | Increase in intracellular concentration of Ca2+ ions and mem... |
| _timestamp | 2011-05-27 13:49:51 |
| created | [InstanceEdit:1299226] Mahajan, SS, 2011-05-22 |
| modified | [InstanceEdit:1306801] Mahajan, SS, 2011-05-27 |
| text | Increase in intracellular concentration of Ca2+ ions and membrane depolarization cooperatively activates BKca, which exhibit large unitary conductance. Ca2+ activated potassium channels. Activation leads to K+ efflux which changes the membrane potential, which leads to inactivation voltage activated Ca2+ channels. BKca are involved in regulation of smooth muscle tone, microbial killing in leukocytes and modulation of neurotransmitter release. Activation of BKca channel with increase in intracellular concentration of Ca2+ leads to efflux of K+ into the extracellular space, which contributes to hyperpolarization of the membrane potential. |
| (summation) | [Reaction:1296037] Activation of Ca2+ activated Potassium channels with large conductance [Homo sapiens] |
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No pathways have been reviewed or authored by Increase in intracellular concentration of Ca2+ ions and mem... (1299225)
