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Details on Person May, B, 2011-05-18

Class:Id	InstanceEdit:1295754
_displayName	May, B, 2011-05-18
_timestamp	2011-05-18 10:44:42
author	[Person:203835] May, Bruce
dateTime	2011-05-18 14:42:29
(created)	[CatalystActivity:1295753] RNA helicase activity of p-4S-UPF1 [cytosol]
(modified)	[Reaction:927789] Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex [Homo sapiens] [Pathway:927802] Nonsense-Mediated Decay (NMD) [Homo sapiens] [BlackBoxEvent:927813] p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A [Homo sapiens] [BlackBoxEvent:927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex [Homo sapiens] [Reaction:927832] UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex [Homo sapiens] [BlackBoxEvent:927836] SMG6 hydrolyzes mRNA with premature termination codon [Homo sapiens] [Reaction:927889] SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) [Homo sapiens] [Pathway:975956] Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) [Homo sapiens] [Pathway:975957] Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) [Homo sapiens]
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No pathways have been reviewed or authored by May, B, 2011-05-18 (1295754)