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Details on Person B-RAF dissociates from S110/S120 p-SPRY2

Class:Id	Reaction:1295604
_displayName	B-RAF dissociates from S110/S120 p-SPRY2
_doRelease	TRUE
_timestamp	2025-02-14 22:03:12
authored	[InstanceEdit:1489508] Rothfels, K, 2011-08-15
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1295600] Rothfels, K, 2011-05-17
input	[Complex:1295587] S110/S120 p-SPRY2:B-RAF [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:934614] Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation
modified	[InstanceEdit:1498835] Rothfels, K, 2011-08-18 [InstanceEdit:1549626] Rothfels, K, 2011-08-30 [InstanceEdit:1580735] Rothfels, K, 2011-09-07 [InstanceEdit:1583046] Rothfels, K, 2011-09-07 [InstanceEdit:1584610] Rothfels, K, 2011-09-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9938452] D'Eustachio, Peter, 2025-02-14
name	B-RAF dissociates from S110/S120 p-SPRY2
output	[EntityWithAccessionedSequence:167224] BRAF [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1295590] p-S110,S120-SPRY2 [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1295634] SPRY2 is serine phosphorylated in response to MAPK activation [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1549563] Gotoh, N, 2011-08-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591321] R-HSA-1295604.3
summation	[Summation:1295591] MAPK-dependent serine phosphorylation of SPRY2 disrupts comp...
(hasEvent)	[Pathway:1295596] Spry regulation of FGF signaling [Homo sapiens]
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No pathways have been reviewed or authored by B-RAF dissociates from S110/S120 p-SPRY2 (1295604)