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Details on Person IL7R is phosphorylated on Y499

Class:IdReaction:1295519
_displayNameIL7R is phosphorylated on Y499
_doReleaseTRUE
_timestamp2017-10-16 09:13:36
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
catalystActivity[CatalystActivity:1295532] non-membrane spanning protein tyrosine kinase activity of IL7:IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:1295522] Jupe, S, 2011-05-17
edited[InstanceEdit:1264800] Jupe, S, 2011-05-06
inferredFrom
input[Complex:9025934] IL7:IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
modified[InstanceEdit:1295755] Jupe, S, 2011-05-18
[InstanceEdit:1963544] Jupe, S, 2011-11-03
[InstanceEdit:1963554] Jupe, S, 2011-11-03
[InstanceEdit:6785154] Jupe, Steve, 2015-06-25
[InstanceEdit:8983043] Duenas, Corina, 2017-03-22
[InstanceEdit:9018973] Duenas, Corina, 2017-09-05
[InstanceEdit:9025936] Jupe, Steve, 2017-10-16
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIL7R is phosphorylated on Y499
output[Complex:1295546] IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2011-12-06
reviewed[InstanceEdit:1963543] Puck, J, 2011-11-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016315] R-HSA-1295519.5
summation[Summation:1295542] Interleukin-7 (IL7) signaling is believed to resemble that o...
(hasEvent)[Pathway:1266695] Interleukin-7 signaling [Homo sapiens]
(precedingEvent)[Reaction:1295516] IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 binds PI3K regulatory subunits [Homo sapiens]
[BlackBoxEvent:9025969] IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780206] Update Tracker - [Reaction:1295519] IL7R is phosphorylated on Y499 - v63:[add_removeInput]
[_UpdateTracker:9780847] Update Tracker - [Reaction:1295519] IL7R is phosphorylated on Y499 - v62:[modifyText]
[_UpdateTracker:9781118] Update Tracker - [Reaction:1295519] IL7R is phosphorylated on Y499 - v61:[modifyText]
[_UpdateTracker:9784394] Update Tracker - [Reaction:1295519] IL7R is phosphorylated on Y499 - v54:[modifyText]
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