Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person FRS2 (also known as FRS2alpha) is broadly expressed in adult...
| Class:Id | Summation:1268219 |
|---|---|
| _displayName | FRS2 (also known as FRS2alpha) is broadly expressed in adult... |
| _timestamp | 2014-12-03 20:42:01 |
| created | [InstanceEdit:1268218] Rothfels, K, 2011-05-09 |
| modified | [InstanceEdit:5654386] Rothfels, Karen, 2014-12-03 |
| text | FRS2 (also known as FRS2alpha) is broadly expressed in adult and fetal tissues. Membrane-bound FRS2 interacts with FGFR as a first step in the phosphorylation of this docking protein. The juxtamembrane binding site for FRS2 does not contain tyrosine, so binding may be independent of receptor activation and/or constitutive. Activation of the FGFR receptor is required for FRS2 phosphorylation and subsequent recruitment of downstream effectors. |
| (summation) | [Reaction:5654399] Activated FGFR2 binds FRS2 [Homo sapiens] [Reaction:5654409] Activated FGFR3 binds FRS2 [Homo sapiens] [Reaction:5654422] Activated FGFR4 binds FRS2 [Homo sapiens] [Reaction:5654569] Activated FGFR1 binds FRS2 [Homo sapiens] |
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No pathways have been reviewed or authored by FRS2 (also known as FRS2alpha) is broadly expressed in adult... (1268219)
