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Details on Person FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl

Class:IdLiteratureReference:1268080
_displayNameFRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl
_timestamp2011-05-09 18:48:07
author[Person:1268077] Wong, A
[Person:1237374] Lamothe, B
[Person:1268079] Lee, A
[Person:111032] Schlessinger, J
[Person:182118] Lax, I
created[InstanceEdit:1268078] Rothfels, K, 2011-05-09
journalProc Natl Acad Sci U S A
pages6684-9
pubMedIdentifier11997436
titleFRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl
volume99
year2002
(literatureReference)[Reaction:5654672] CBL ubiquitinates FRS2 and FGFR1 [Homo sapiens]
[Reaction:5654673] p-CBL:GRB2 binds p-FRS2:activated FGFR1 [Homo sapiens]
[Reaction:5654677] CBL ubiquitinates FRS2 and FGFR2 [Homo sapiens]
[Reaction:5654679] CBL ubiquitinates FRS2 and FGFR3 [Homo sapiens]
[Reaction:5654684] CBL ubiquitinates FRS2 and FGFR4 [Homo sapiens]
[Pathway:5654726] Negative regulation of FGFR1 signaling [Homo sapiens]
[Pathway:5654727] Negative regulation of FGFR2 signaling [Homo sapiens]
[Reaction:5654729] p-CBL:GRB2 binds p-FRS2:activated FGFR2 [Homo sapiens]
[Reaction:5654730] p-CBL:GRB2 binds p-FRS2:activated FGFR3 [Homo sapiens]
[Pathway:5654732] Negative regulation of FGFR3 signaling [Homo sapiens]
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