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Details on Person FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

Class:IdLiteratureReference:1267786
_displayNameFLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
_timestamp2011-05-09 04:32:38
author[Person:1267783] Pop, Cristina
[Person:1267785] Oberst, A
[Person:1267788] Drag, M
[Person:1267784] Van Raam, BJ
[Person:1247963] Riedl, SJ
[Person:1267787] Green, DR
[Person:141140] Salvesen, Guy S.
created[InstanceEdit:1267789] Shamovsky, V, 2011-05-09
journalBiochem J
pages447-57
pubMedIdentifier21235526
titleFLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
volume433
year2011
(literatureReference)[Summation:140942] The inflammatory cytokine tumor necrosis factor alpha (TNF-α...
[Summation:1267834] Induction of inflammatory cytokines in response to poly(I:C)...
[Summation:3465328] In the presence of FLIP(L), both caspase-8 and FLIP(L) are r...
[Summation:5433115] Receptor-interacting serine/threonine-protein kinase 1 (RIPK...
[Summation:9697743] The balance between caspase-dependent apoptosis and RIPK-dep...
[Summation:9697744] Receptor-interacting serine/threonine-protein kinase 1 (RIPK...
[Pathway:3371378] Regulation by c-FLIP [Homo sapiens]
[Reaction:3465429] FLIP(S) and procaspase-8 form heterodimer [Homo sapiens]
[BlackBoxEvent:3465448] Caspase-8 and FLIP(L) processing at DISC [Homo sapiens]
[Reaction:5675456] FLIP(L) and procaspase-8 form heterodimer [Homo sapiens]
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