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Details on Person ESR1 dimer:ESTG [nucleoplasm]

Class:Id	Complex:1254381
_displayName	ESR1 dimer:ESTG [nucleoplasm]
_timestamp	2020-12-21 10:54:32
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1254385] Orlic-Milacic, Marija, 2011-04-29
hasComponent	[Complex:1254384] ESR1 homodimer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:446168] ESR1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:446168] ESR1 [nucleoplasm] [Homo sapiens] [SimpleEntity:1254400] ESTG [nucleoplasm] [SimpleEntity:1254400] ESTG [nucleoplasm]
isChimeric	FALSE
modified	[InstanceEdit:9012288] Rothfels, Karen, 2017-07-12 [InstanceEdit:9710005] Jassal, Bijay, 2020-12-21
name	ESR1 dimer:ESTG
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2017586] R-HSA-1254381.3
(activeUnit)	[NegativeGeneExpressionRegulation:8932074] Negative gene expression regulation by 'ESR1:estrogen:AXIN1 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:8939947] Positive gene expression regulation by 'ESR1:estrogen:RUNX2 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9011946] Positive gene expression regulation by 'CCND1 gene:nucleosome:ESR1:ESTG [nucleoplasm]' [PositiveGeneExpressionRegulation:9011951] Positive gene expression regulation by 'GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm]' [PositiveGeneExpressionRegulation:9011965] Positive gene expression regulation by 'KDM4B gene:nucleoplasm:ESR1:ESTG [nucleoplasm]' [PositiveGeneExpressionRegulation:9011977] Positive gene expression regulation by 'MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm]' [PositiveGeneExpressionRegulation:9011994] Positive gene expression regulation by 'MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm]' [PositiveGeneExpressionRegulation:9018527] Positive gene expression regulation by 'EBAG9 gene:ESR1:ESTG [nucleoplasm]'
(hasComponent)	[Complex:1254397] ERBB4s80:ESR1:estrogen [nucleoplasm] [Homo sapiens] [Complex:8931986] RUNX1:CBFB:ESR1:estrogen [nucleoplasm] [Homo sapiens] [Complex:8932051] ESR1:estrogen:AXIN1 gene [nucleoplasm] [Homo sapiens] [Complex:8939910] ESR1:estrogen:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:9009370] ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] [Homo sapiens] [Complex:9009373] ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] [Homo sapiens] [Complex:9011878] MYC gene:nucleoplasm:ESR1:ESTG [nucleoplasm] [Homo sapiens] [Complex:9011883] MYC gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300:NCOA3 [nucleoplasm] [Homo sapiens] [Complex:9011887] MYC gene:ESR1:ESTG:JUND:FOSB:Cohesin Complex [nucleoplasm] [Homo sapiens] [Complex:9011891] MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] [Homo sapiens] List all 26 refering instances
(hasMember)	[DefinedSet:9710004] ESR multimer:ESTG [nucleoplasm] [Homo sapiens]
(input)	[Reaction:1254386] ERBB4s80 forms a complex with estrogen receptor ESR1 [Homo sapiens] [Reaction:8931981] RUNX1 binds ESR1 [Homo sapiens] [Reaction:8932070] ESR1 binds the AXIN1 gene [Homo sapiens] [Reaction:8939904] Activated ESR1 binds the RUNX2 gene promoter [Homo sapiens] [Reaction:9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers [Homo sapiens] [Reaction:9011983] Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes [Homo sapiens] [Reaction:9011997] ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter [Homo sapiens] [Reaction:9018325] ESR1:ESTG binds CXXC5 gene [Homo sapiens] [Reaction:9018499] ESR1:ESTG and EP300 are recruited to TFF3 promoter [Homo sapiens] [Reaction:9018503] ESR1:ESTG bind the EBAG9 5' region [Homo sapiens] List all 14 refering instances
(updatedInstance)	[_UpdateTracker:9897773] Update Tracker - [Complex:1254381] ESR1 dimer:ESTG [nucleoplasm] - v62:[modifyName] [_UpdateTracker:9902046] Update Tracker - [Complex:1254381] ESR1 dimer:ESTG [nucleoplasm] - v76:[modifyName]
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No pathways have been reviewed or authored by ESR1 dimer:ESTG [nucleoplasm] (1254381)