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Details on Person TIM23 SORT complex inserts proteins into inner membrane
Class:Id Reaction:1252249 _displayName TIM23 SORT complex inserts proteins into inner membrane _doRelease TRUE _timestamp 2014-02-06 21:34:21 authored [InstanceEdit:1252340] May, B, 2011-04-27 catalystActivity [CatalystActivity:1258365] membrane insertase activity of TIM23 SORT:Cargo [mitochondrial inner membrane] catalystActivityReference [CatalystActivityReference:9643196] membrane insertase activity of TIM23 SORT:Cargo [mitochondrial inner membrane] Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria compartment [Compartment:70616] mitochondrial inner membrane created [InstanceEdit:1252251] May, B, 2011-04-27 edited [InstanceEdit:1252340] May, B, 2011-04-27 input [Complex:1268011] TIM23 SORT:Cargo [mitochondrial inner membrane] [Saccharomyces cerevisiae] isChimeric FALSE literatureReference [LiteratureReference:1252351] Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria [LiteratureReference:1252350] Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import [LiteratureReference:1252348] Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria [LiteratureReference:1252368] Modular structure of the TIM23 preprotein translocase of mitochondria [LiteratureReference:1252356] Different import pathways through the mitochondrial intermembrane space for inner membrane proteins [LiteratureReference:1252319] Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway [LiteratureReference:1252367] Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23 [LiteratureReference:1252376] Tim50, a novel component of the TIM23 preprotein translocase of mitochondria [LiteratureReference:1252357] The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44 [LiteratureReference:1252293] A cooperative action of the ATP-dependent import motor complex and the inner membrane potential drives mitochondrial preprotein import [LiteratureReference:1254306] Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain [LiteratureReference:1258360] Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism [LiteratureReference:1258382] Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17 [LiteratureReference:1258397] Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting [LiteratureReference:1258358] Motor-free mitochondrial presequence translocase drives membrane integration of preproteins modified [InstanceEdit:1252340] May, B, 2011-04-27 [InstanceEdit:1254318] May, B, 2011-04-29 [InstanceEdit:1254375] May, B, 2011-04-29 [InstanceEdit:1258391] May, B, 2011-05-03 [InstanceEdit:1268018] May, B, 2011-05-09 [InstanceEdit:1977303] May, B, 2011-11-08 [InstanceEdit:2010553] May, B, 2011-11-22 [InstanceEdit:2108992] May, B, 2012-02-12 [InstanceEdit:2127546] May, B, 2012-02-15 [InstanceEdit:5257491] May, B, 2014-02-06 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name TIM23 SORT complex inserts proteins into inner membrane output [DefinedSet:1268000] Cargo of TIM23 SORT [mitochondrial inner membrane] [Saccharomyces cerevisiae] [Complex:1252229] TIM23 Complex [mitochondrial inner membrane] [Saccharomyces cerevisiae] precedingEvent
releaseDate 2012-03-13 reviewed [InstanceEdit:1914221] D'Eustachio, P, 2011-11-01 [InstanceEdit:2108993] Endo, T, 2012-02-12 reviewStatus [ReviewStatus:9821382] five stars species [Species:68322] Saccharomyces cerevisiae stableIdentifier [StableIdentifier:2158125] R-SCE-1252249.3 summation [Summation:1258370] The TIM23 Complex resides in the inner membrane of the mitoc... (inferredFrom) [Reaction:1299482] TIMM23 SORT inserts proteins into inner membrane [Homo sapiens] (replacementInstances) [_Deleted:9697205] Deletion of instance: 1252265
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