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Details on Person Translocation of ERBB4s80 to the nucleus

Class:Id	BlackBoxEvent:1252013
_displayName	Translocation of ERBB4s80 to the nucleus
_doRelease	TRUE
_timestamp	2019-03-05 19:37:20
authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:9638819] Stern, David F, 2019-02-21
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:1252011] Orlic-Milacic, Marija, 2011-04-26
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07 [InstanceEdit:9638824] Orlic-Milacic, Marija, 2019-03-05
input	[DefinedSet:1251980] ERBB4s80 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1252005] gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase [LiteratureReference:9612232] Nuclear ErbB4 signaling through H3K9me3 is antagonized by EGFR-activated c-Src
modified	[InstanceEdit:1493133] Orlic-Milacic, Marija, 2011-08-15 [InstanceEdit:1549550] Orlic-Milacic, Marija, 2011-08-29 [InstanceEdit:1843097] Orlic-Milacic, M, 2011-10-27 [InstanceEdit:1977294] Orlic-Milacic, M, 2011-11-07 [InstanceEdit:1979912] Orlic-Milacic, M, 2011-11-08 [InstanceEdit:2104984] Orlic-Milacic, M, 2012-02-08 [InstanceEdit:9607247] Orlic-Milacic, Marija, 2018-05-01 [InstanceEdit:9612236] Orlic-Milacic, Marija, 2018-06-27 [InstanceEdit:9638822] Orlic-Milacic, Marija, 2019-03-05 [InstanceEdit:9638825] Orlic-Milacic, Marija, 2019-03-05 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of ERBB4s80 to the nucleus
output	[DefinedSet:1252016] ERBB4s80 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:1251997] Cleavage of ERBB4m80 by gamma-scretase complex [Homo sapiens] [Reaction:1251992] Cleavage of P-ERBB4jmA isoforms by ADAM17 [Homo sapiens]
regulatedBy	[NegativeRegulation:9612229] Negative regulation by 'ERBB4s80:MyrG-p-Y419-SRC [plasma membrane]'
releaseDate	2011-12-06
reviewed	[InstanceEdit:1979910] Harris, RC, 2011-11-11 [InstanceEdit:1979909] Zeng, F, 2011-11-11 [InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016124] R-HSA-1252013.5
summation	[Summation:1252012] The soluble intracellular domain of ERBB4 s80 (E4ICD) is abl...
(hasEvent)	[Pathway:1251985] Nuclear signaling by ERBB4 [Homo sapiens]
(precedingEvent)	[Reaction:1254386] ERBB4s80 forms a complex with estrogen receptor ESR1 [Homo sapiens] [Reaction:9612246] ERBB4s80 binds the APOE gene [Homo sapiens] [Reaction:9612255] ERBB4s80 binds ADAP1 gene [Homo sapiens] [Reaction:9612278] ERBB4s80 binds SPARC gene [Homo sapiens] [Reaction:9612440] ERBB4s80 binds the MXD4 gene [Homo sapiens] [Reaction:9612444] ERBB4s80 binds STMN1 gene [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779035] Update Tracker - [BlackBoxEvent:1252013] Translocation of ERBB4s80 to the nucleus - v66:[addLiteratureReference, addRegulator, modifyText]
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