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Details on Person TXNIP is released from oxidized thioredoxin

Class:Id	Reaction:1250253
_displayName	TXNIP is released from oxidized thioredoxin
_doRelease	TRUE
_timestamp	2020-01-07 13:41:22
authored	[InstanceEdit:1253354] Jupe, S, 2011-04-28
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1250252] Jupe, S, 2011-04-15
edited	[InstanceEdit:1253354] Jupe, S, 2011-04-28
inferredFrom	[Reaction:1250256] Txnip is released from oxidized thioredoxin [Mus musculus]
input	[Complex:1250249] Oxidized thioredoxin:TXNIP [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:1252399] Jupe, S, 2011-04-27 [InstanceEdit:1253356] Jupe, S, 2011-04-28 [InstanceEdit:1254262] Jupe, S, 2011-04-28 [InstanceEdit:1361858] Jupe, S, 2011-06-06 [InstanceEdit:1361865] Jupe, S, 2011-06-06 [InstanceEdit:9673431] Murillo, Julieth, 2020-01-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TXNIP is released from oxidized thioredoxin
output	[EntityWithAccessionedSequence:73668] 2xHC-TXN [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:1250246] TXNIP [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1250280] ROS oxidize thioredoxin [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1253355] Kufer, TA, 2011-04-28 [InstanceEdit:1361863] Rittinger, K, 2011-06-06 [InstanceEdit:1361862] Wong, Edmond, 2011-06-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357644] R-HSA-1250253.3
summation	[Summation:1250271] ROS induce the dissociation of TXNIP from thioredoxin, freei...
(hasEvent)	[Pathway:844456] The NLRP3 inflammasome [Homo sapiens] [Pathway:9660826] Purinergic signaling in leishmaniasis infection [Homo sapiens]
(precedingEvent)	[Reaction:1250264] TXNIP binds reduced thioredoxin [Homo sapiens]
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No pathways have been reviewed or authored by TXNIP is released from oxidized thioredoxin (1250253)