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Details on Person p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane]
Class:Id Complex:1250194
_displayName p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane]
_timestamp 2012-04-27 18:36:05
compartment [Compartment:876] plasma membrane
created [InstanceEdit:1250197] Orlic-Milacic, Marija, 2011-04-14
hasComponent
isChimeric FALSE
modified [InstanceEdit:1474193] Orlic-Milacic, Marija, 2011-08-05 [InstanceEdit:1963602] Orlic-Milacic, M, 2011-11-03 [InstanceEdit:2000338] Orlic-Milacic, M, 2011-11-21 [InstanceEdit:2213009] Matthews, L, 2012-04-27
name p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:2017575] R-HSA-1250194.1
(hasComponent) [Complex:1250479] GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] [Homo sapiens]
(input) [Reaction:1250486] Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers [Homo sapiens]
(normalEntity) [EntityFunctionalStatus:9655375] gain_of_function of Phosphorylated ERBB2 L755S,(ERBB2 L755M,ERBB2 L755W) heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655388] gain_of_function of Phosphorylated ERBB2 L755P heterodimers:p-Y349,350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655639] gain_of_function of Phosphorylated ERBB2 V777L,(ERBB2 V777M,ERBB2 V777E) heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655640] gain_of_function of Phosphorylated ERBB2 T798I,ERBB2 T798M,(ERBB2 T733I) heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655641] gain_of_function of Phosphorylated ERBB2 H878Y,(ERBB2 H878R) heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655642] gain_of_function of Phosphorylated ERBB2 T862A heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655644] gain_of_function of Phosphorylated ERBB2 D769H,(ERBB2 D769Y,ERBB2 D769N) heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655645] gain_of_function of Phosphorylated P780_Y781insGSP heterodimers: p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655646] gain_of_function of Phosphorylated ERBB2 V842I,(ERBB2 V842E) heterodimers:p-Y349,Y350-SHC1 [plasma membrane] [EntityFunctionalStatus:9655647] gain_of_function of Phosphorylated ERBB2 I767M heterodimers:p-Y349,Y350-SHC1 [plasma membrane]
(output) [Reaction:1250195] SHC1 phosphorylation by ERBB2 heterodimers [Homo sapiens]
(updatedInstance) [_UpdateTracker:9871849] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v41:[removeCompartment, updateContainedComponent] [_UpdateTracker:9873150] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v42:[updateContainedComponent] [_UpdateTracker:9876728] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v44:[updateContainedComponent] [_UpdateTracker:9888492] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v46:[updateContainedComponent] [_UpdateTracker:9893044] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v54:[updateContainedComponent] [_UpdateTracker:9894670] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v57:[updateContainedComponent] [_UpdateTracker:9895813] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v59:[updateContainedComponent] [_UpdateTracker:9900811] Update Tracker - [Complex:1250194] p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v70:[updateContainedComponent]
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No pathways have been reviewed or authored by p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (1250194)