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Details on Person SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane]

Class:IdComplex:1248746
_displayNameSHC1:Phosphorylated ERBB2 heterodimers [plasma membrane]
_timestamp2012-04-27 18:34:25
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1248751] Orlic-Milacic, Marija, 2011-04-13
hasComponent
modified[InstanceEdit:1250213] Orlic-Milacic, Marija, 2011-04-14
[InstanceEdit:1280208] Orlic-Milacic, Marija, 2011-05-12
[InstanceEdit:1368197] Orlic-Milacic, Marija, 2011-06-30
[InstanceEdit:1474193] Orlic-Milacic, Marija, 2011-08-05
[InstanceEdit:1963627] Orlic-Milacic, M, 2011-11-03
[InstanceEdit:2000337] Orlic-Milacic, M, 2011-11-21
[InstanceEdit:2213009] Matthews, L, 2012-04-27
nameSHC1:Phosphorylated ERBB2 heterodimers
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016982] R-HSA-1248746.1
(input)[Reaction:1250195] SHC1 phosphorylation by ERBB2 heterodimers [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:9655368] gain_of_function of Phosphorylated ERBB2 L755S,(ERBB2 L755M,ERBB2 L755W) heterodimers:SHC1 [cytosol]
[EntityFunctionalStatus:9655386] gain_of_function of Phosphorylated ERBB2 L755P heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655462] gain_of_function of Phosphorylated ERBB2 H878Y,(ERBB2 H878R) heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655463] gain_of_function of Phosphorylated ERBB2 L869R,(ERBB2 L869Q) heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655465] gain_of_function of Phosphorylated ERBB2 R896C,(ERBB2 R896H) heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655466] increased_translational_product_level of p-ERBB2 homodimer:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655467] gain_of_function of Phosphorylated P780_Y781insGSP heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655468] gain_of_function of Phosphorylated ERBB2 D769H,(ERBB2 D769Y,ERBB2 D769N) heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655469] gain_of_function of Phosphorylated ERBB2 I767M heterodimers:SHC1 [plasma membrane]
[EntityFunctionalStatus:9655470] gain_of_function of Phosphorylated ERBB2 T862A heterodimers:SHC1 [plasma membrane]
List all 17 refering instances
(output)[Reaction:1963578] SHC1 binds phosphorylated ERBB2 heterodimers [Homo sapiens]
(physicalEntity)[CatalystActivity:1250198] protein tyrosine kinase activity of SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane]
(updatedInstance)[_UpdateTracker:9872166] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v41:[removeCompartment, updateContainedComponent]
[_UpdateTracker:9873308] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v42:[updateContainedComponent]
[_UpdateTracker:9878698] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v44:[updateContainedComponent]
[_UpdateTracker:9888069] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v46:[updateContainedComponent]
[_UpdateTracker:9892771] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v54:[updateContainedComponent]
[_UpdateTracker:9894403] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v57:[updateContainedComponent]
[_UpdateTracker:9895412] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v59:[updateContainedComponent]
[_UpdateTracker:9900758] Update Tracker - [Complex:1248746] SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] - v70:[updateContainedComponent]
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No pathways have been reviewed or authored by SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (1248746)
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