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Details on Person Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma
| Class:Id | LiteratureReference:1248643 |
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| _displayName | Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma |
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| _timestamp | 2011-04-11 14:38:36 |
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| author | [Person:1248634] Huang, PH
[Person:1248641] Mukasa, A
[Person:1248622] Bonavia, R
[Person:1248627] Flynn, RA
[Person:1248624] Brewer, ZE
[Person:187394] Cavenee, WK
[Person:1248630] Furnari, FB
[Person:1248644] White, FM |
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| created | [InstanceEdit:1248642] Orlic-Milacic, Marija, 2011-04-11 |
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| journal | Proc Natl Acad Sci U S A |
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| pages | 12867-72 |
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| pubMedIdentifier | 17646646 |
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| title | Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma |
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| volume | 104 |
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| year | 2007 |
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| (literatureReference) | [Reaction:1225947] Binding of SHC1 to p-6Y-EGFR mutants [Homo sapiens]
[Reaction:1225950] Binding of GRB2:SOS1 complex to phosphorylated ligand-responsive EGFR mutants [Homo sapiens]
[Reaction:1226016] Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants [Homo sapiens]
[Reaction:1248655] Trans-autophosphorylation of EGFRvIII mutant dimers [Homo sapiens]
[Reaction:5637764] Binding of GRB2:GAB1 complex to p-EGFRvIII mutant [Homo sapiens]
[Reaction:5637766] Binding of SHC1 to p-5Y-EGFRvIII [Homo sapiens]
[Reaction:5637770] Binding of GRB2:SOS1 complex to phosphorylated EGFRvIII [Homo sapiens]
[Summation:1181246] Signaling by EGFR is frequently activated in cancer through ... |
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