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Details on Person ERBB3 binds neuregulins

Class:Id	Reaction:1247497
_displayName	ERBB3 binds neuregulins
_doRelease	TRUE
_timestamp	2011-11-23 11:07:02
authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:1247496] Orlic-Milacic, Marija, 2011-04-01
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07
input	[EntityWithAccessionedSequence:372885] ERBB3-1 [plasma membrane] [Homo sapiens] [DefinedSet:1227956] NRG1/2 [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1247834] ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms
modified	[InstanceEdit:1247835] Orlic-Milacic, Marija, 2011-04-07 [InstanceEdit:1370839] Orlic-Milacic, Marija, 2011-07-04 [InstanceEdit:1972362] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:2006492] Orlic-Milacic, M, 2011-11-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERBB3 binds neuregulins
output	[Complex:1247495] NRG1/2:ERBB3 [plasma membrane] [Homo sapiens]
releaseDate	2011-12-06
reviewed	[InstanceEdit:1972347] Neckers, LM, 2011-11-11 [InstanceEdit:1972346] Xu, W, 2011-11-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016203] R-HSA-1247497.2
summation	[Summation:1370826] ERBB3 becomes activated by binding either neuregulin 1 (NRG1...
(hasEvent)	[Pathway:1227986] Signaling by ERBB2 [Homo sapiens]
(precedingEvent)	[Reaction:1247500] ERBB2 forms a heterodimer with activated ERBB3 [Homo sapiens] [Reaction:1963589] ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 [Homo sapiens] [Reaction:1977958] ERBB4 forms heterodimers with ERBB3 [Homo sapiens]
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No pathways have been reviewed or authored by ERBB3 binds neuregulins (1247497)