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Details on Person DNA-(apurinic or apyrimidinic site) endonuclease activity

Class:Id	GO_MolecularFunction:12450
_displayName	DNA-(apurinic or apyrimidinic site) endonuclease activity
_timestamp	2009-11-21 18:35:32
accession	0003906
definition	Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).
ecNumber	4.2.99.18
modified	[InstanceEdit:160533] Schmidt, EE, 2005-03-23 05:24:35 [InstanceEdit:162334] Schmidt, EE, 2005-03-23 05:45:22 [InstanceEdit:162607] Schmidt, EE, 2005-04-01 11:06:09 [InstanceEdit:171322] Schmidt, EE, 2006-02-06 10:50:16 [InstanceEdit:258122] Kanapin, EE, 2008-03-27 12:15:20 [InstanceEdit:357819] Kanapin, EE, 2008-06-18 10:45:39 [InstanceEdit:376438] Kanapin, EE, 2008-09-08 10:23:04 [InstanceEdit:383393] Kanapin, AA, 2008-11-26 13:49:44 [InstanceEdit:396309] Kanapin, EE, 2009-03-09 13:26:57 [InstanceEdit:422569] Kanapin, EE [InstanceEdit:423222] Kanapin, AA [InstanceEdit:436347] Kanapin, EE [InstanceEdit:447572] Kanapin, EE [InstanceEdit:448165] Kanapin, AA [InstanceEdit:526073] Kanapin, AA [InstanceEdit:528085] Kanapin, AA [InstanceEdit:615500] Kanapin, AA [InstanceEdit:797782] Kanapin, AA [InstanceEdit:937668] Yung, CK [InstanceEdit:938674] Yung, CK [InstanceEdit:1042299] Yung, CK [InstanceEdit:1043152] Yung, CK [InstanceEdit:1220942] Yung, CK [InstanceEdit:1221553] Yung, CK [InstanceEdit:1301009] Yung, CK [InstanceEdit:1301023] Yung, CK [InstanceEdit:1301626] Yung, CK [InstanceEdit:1552540] Yung, CK [InstanceEdit:1552982] Yung, CK [InstanceEdit:1996004] Yung, CK [InstanceEdit:1996190] Yung, CK [InstanceEdit:2132408] Weiser, JD [InstanceEdit:2133145] Weiser, JD [InstanceEdit:2133759] Yung, CK [InstanceEdit:2133760] Yung, CK [InstanceEdit:2133761] Yung, CK [InstanceEdit:2266115] Yung, CK [InstanceEdit:2266117] Yung, CK [InstanceEdit:2266118] Weiser, JD [InstanceEdit:2266147] Weiser, JD [InstanceEdit:2267216] Yung, CK [InstanceEdit:2454362] Weiser, JD [InstanceEdit:2455542] Weiser, JD [InstanceEdit:2455544] Yung, CK [InstanceEdit:2587907] Weiser, JD [InstanceEdit:2588510] Yung, CK [InstanceEdit:3132285] Weiser, JD [InstanceEdit:3132714] Yung, CK [InstanceEdit:3445953] Weiser, JD [InstanceEdit:3446290] Yung, CK [InstanceEdit:4341211] Weiser, JD [InstanceEdit:4341654] Yung, CK [InstanceEdit:5083267] Weiser, JD [InstanceEdit:5083619] Yung, CK [InstanceEdit:5263134] Weiser, JD [InstanceEdit:5263568] Yung, CK [InstanceEdit:5433708] Yung, CK [InstanceEdit:5619033] Yung, CK [InstanceEdit:5634717] Yung, CK [InstanceEdit:5673679] Yung, CK [InstanceEdit:5692203] Yung, CK [InstanceEdit:6792433] Yung, CK [InstanceEdit:6808304] Yung, CK [InstanceEdit:8857520] Yung, CK [InstanceEdit:8870260] Yung, CK [InstanceEdit:8935677] Yung, CK [InstanceEdit:8945685] Yung, CK [InstanceEdit:8978846] Yung, CK [InstanceEdit:9005311] Weiser, JD [InstanceEdit:9016044] Weiser, JD [InstanceEdit:9607871] Weiser, JD [InstanceEdit:9608015] Weiser, JD [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17
name	DNA-(apurinic or apyrimidinic site) endonuclease activity
referenceDatabase	[ReferenceDatabase:1] GO
(activity)	[CatalystActivity:110374] DNA-(apurinic or apyrimidinic site) endonuclease activity of POLB [nucleoplasm] [CatalystActivity:5266440] DNA-(apurinic or apyrimidinic site) endonuclease activity of hydrolase [cytoplasm] [CatalystActivity:5649543] DNA-(apurinic or apyrimidinic site) endonuclease activity of POLB:APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm] [CatalystActivity:5649717] DNA-(apurinic or apyrimidinic site) endonuclease activity of NEIL1,NEIL2:AP-dsDNA [nucleoplasm] [CatalystActivity:5649731] DNA-(apurinic or apyrimidinic site) endonuclease activity of NEIL1:NEIL2:POLB:SSB(3'Pi-5'dRP)-dsDNA [nucleoplasm]
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No pathways have been reviewed or authored by DNA-(apurinic or apyrimidinic site) endonuclease activity (12450)