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Details on Person Transamination of MOB to methionine

Class:Id	Reaction:1237102
_displayName	Transamination of MOB to methionine
_doRelease	TRUE
_timestamp	2026-02-16 16:44:32
authored	[InstanceEdit:1237120] Stephan, R, 2010-10-24
catalystActivity	[CatalystActivity:1295495] transaminase activity of PXLP-K259-GOT1 dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1237104] Jassal, B, 2011-03-30
crossReference	[DatabaseIdentifier:9929694] RHEA:31765
edited	[InstanceEdit:1237104] Jassal, B, 2011-03-30
goBiologicalProcess	[GO_BiologicalProcess:528453] L-methionine salvage
inferredFrom	[Reaction:1237106] Transamination of MOB to methionine [Crithidia fasciculata]
input	[SimpleEntity:1237122] 4MTOBUTA [cytosol] [SimpleEntity:8942986] L-amino acid [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:1237089] Methionine regeneration and aspartate aminotransferase in parasitic protozoa
modified	[InstanceEdit:1237190] Jassal, B, 2011-03-30 [InstanceEdit:1237556] Jassal, B, 2011-03-31 [InstanceEdit:1243078] Jassal, B, 2011-03-31 [InstanceEdit:1295491] Jassal, B, 2011-05-16 [InstanceEdit:1295494] Jassal, B, 2011-05-16 [InstanceEdit:1299385] Jassal, B, 2011-05-23 [InstanceEdit:1299491] Jassal, B, 2011-05-23 [InstanceEdit:5255454] D'Eustachio, Peter, 2014-02-06 [InstanceEdit:8943735] D'Eustachio, Peter, 2016-10-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9929687] D'Eustachio, Peter, 2024-11-27 [InstanceEdit:9982317] D'Eustachio, Peter, 2026-02-16
name	Transamination of MOB to methionine 4-methylsulfanyl-2-oxobutanoate + an L-alpha-amino acid => a 2-oxocarboxylate + L-methionine
output	[SimpleEntity:174390] L-Met [cytosol] [SimpleEntity:1237175] 2-Oxoacid [cytosol]
precedingEvent	[Reaction:1237119] Acireductone is oxidized to MOB [Homo sapiens] [Reaction:1237129] Acireductone is created [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1299489] D'Eustachio, P, 2011-05-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357543] R-HSA-1237102.5
summation	[Summation:1237103] In the last step MOB is transaminated to methionine. The rea...
(hasEvent)	[Pathway:1237112] Methionine salvage pathway [Homo sapiens]
(precedingEvent)	[Reaction:174391] MAT1A multimers transfer Ado from ATP to L-Met [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782272] Update Tracker - [Reaction:1237102] Transamination of MOB to methionine - v59:[add_removeInput] [_UpdateTracker:9939827] Update Tracker - [Reaction:1237102] Transamination of MOB to methionine - v92:[modifyText]
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