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Details on Person Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide

Class:Id	Reaction:1237081
_displayName	Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide
_doRelease	TRUE
_timestamp	2014-02-05 16:03:47
authored	[InstanceEdit:1237008] May, B, 2011-03-24
catalystActivity	[CatalystActivity:1237060] carbonate dehydratase activity of CA6:Zinc [extracellular region]
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:1237041] May, B, 2011-03-30
edited	[InstanceEdit:1237008] May, B, 2011-03-24
input	[SimpleEntity:351626] H+ [extracellular region] [SimpleEntity:425425] HCO3- [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:1237504] Gustin from human parotid saliva is carbonic anhydrase VI [LiteratureReference:1237473] Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines [LiteratureReference:1237495] Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors [LiteratureReference:1243058] Structure and mechanism of carbonic anhydrase
modified	[InstanceEdit:1237538] May, B, 2011-03-31 [InstanceEdit:1243071] May, B, 2011-03-31 [InstanceEdit:1244338] May, B, 2011-04-01 [InstanceEdit:2252566] May, B, 2012-05-16 [InstanceEdit:5252140] May, B, 2014-02-05 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide H+ + HCO3- -> H2O + CO2
output	[SimpleEntity:1237009] CO2 [extracellular region] [SimpleEntity:109276] H2O [extracellular region]
releaseDate	2012-06-12
reverseReaction	[Reaction:1237045] Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton [Homo sapiens] [Reaction:1237081] Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide [Homo sapiens]
reviewed	[InstanceEdit:2252565] Jassal, B, 2012-05-16 [InstanceEdit:2252567] Silverman, DN, 2012-05-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294691] R-HSA-1237081.2
summation	[Summation:1244349] Carbonic anhydrase VI (CA6) dehydrates bicarbonate to yield ...
(hasEvent)	[Pathway:1237061] Individual Reactions Catalyzed by Carbonic Anhydrases [Homo sapiens] [Pathway:1475029] Reversible hydration of carbon dioxide [Homo sapiens]
(reverseReaction)	[Reaction:1237045] Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton [Homo sapiens]
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No pathways have been reviewed or authored by Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide (1237081)