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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person EGFR L747_T751delinsP [plasma membrane]

Class:IdEntityWithAccessionedSequence:1228012
_displayNameEGFR L747_T751delinsP [plasma membrane]
_timestamp2018-11-08 14:29:54
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1228014] Orlic-Milacic, Marija, 2011-03-16
crossReference[DatabaseIdentifier:1655506] COSMIC:COSM24573
[DatabaseIdentifier:1655507] COSMIC:COSV51765856
[DatabaseIdentifier:1655510] COSMIC:COSV51803491
disease[Disease:1247848] non-small cell lung carcinoma
[Disease:1500689] cancer
[Disease:1500699] lung cancer
endCoordinate1210
hasModifiedResidue[FragmentReplacedModification:9628407] Replacement of residues 747 to 751 by P
literatureReference[LiteratureReference:1181048] EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
modified[InstanceEdit:1247850] Orlic-Milacic, Marija, 2011-04-07
[InstanceEdit:1248671] Orlic-Milacic, Marija, 2011-04-11
[InstanceEdit:1655512] Orlic-Milacic, Marija, 2011-10-12
[InstanceEdit:1655513] Orlic-Milacic, Marija, 2011-10-12
[InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
[InstanceEdit:9628406] Orlic-Milacic, Marija, 2018-11-08
nameEGFR L747_T751delinsP
Epidermal Growth Factor Receptor L747_T751delinsP
EGFR Leu747_Thr751delinsPro
EGFR L747_T751>P
referenceEntity[ReferenceGeneProduct:54208] UniProt:P00533 EGFR [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2017559] R-HSA-1228012.2
startCoordinate25
(hasCandidate)[CandidateSet:1176052] Ligand-responsive EGFR mutants sensitive to non-covalent TKIs [plasma membrane] [Homo sapiens]
[CandidateSet:1182964] EGFR L747_A750del spanning mutants [plasma membrane] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9887853] Update Tracker - [EntityWithAccessionedSequence:1228012] EGFR L747_T751delinsP [plasma membrane] - v46:[modifyName]
[_UpdateTracker:9899886] Update Tracker - [EntityWithAccessionedSequence:1228012] EGFR L747_T751delinsP [plasma membrane] - v67:[add_removeHasModifiedResidue]
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No pathways have been reviewed or authored by EGFR L747_T751delinsP [plasma membrane] (1228012)