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Details on Person Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90
| Class:Id | LiteratureReference:1227977 |
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| _displayName | Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90 |
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| _timestamp | 2011-03-15 17:17:07 |
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| author | [Person:1227984] Xu, Wanping
[Person:1227980] Mimnaugh, E
[Person:1227976] Rosser, MF
[Person:1227975] Nicchitta, C
[Person:1227974] Marcu, M
[Person:182999] Yarden, Y
[Person:1227979] Neckers, Leonard |
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| created | [InstanceEdit:1227973] Orlic-Milacic, Marija, 2011-03-15 |
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| journal | J Biol Chem |
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| pages | 3702-8 |
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| pubMedIdentifier | 11071886 |
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| title | Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90 |
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| volume | 276 |
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| year | 2001 |
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| (literatureReference) | [Reaction:1227971] Association of mature ERBB2 with HSP90 chaperone and its co-chaperone CDC37 [Homo sapiens]
[Reaction:1963589] ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 [Homo sapiens]
[Summation:1227965] ERBB2, present at low levels in normal cells, is overexpress...
[Summation:1227969] Mature ERBB2 requires continual association with HSP90 and C... |
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