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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person FGFR3b S249C [plasma membrane]

Class:IdEntityWithAccessionedSequence:1226109
_displayNameFGFR3b S249C [plasma membrane]
_timestamp2014-11-20 17:29:21
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1226104] Rothfels, K, 2011-03-08
crossReference[DatabaseIdentifier:2023342] COSMIC:COSV53390026
[DatabaseIdentifier:2023326] COSMIC:COSM29427
disease[Disease:1493885] bladder carcinoma
[Disease:2032940] bone development disease
[Disease:1500689] cancer
[Disease:1614672] cervical cancer
[Disease:1248679] head and neck squamous cell carcinoma
[Disease:1655499] prostate cancer
[Disease:1625209] thanatophoric dysplasia
endCoordinate806
hasModifiedResidue[ReplacedResidue:1226108] L-serine 249 replaced with L-cysteine
literatureReference[LiteratureReference:1226112] Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
[LiteratureReference:2064376] Another mutation that results in the substitution of an unpaired cysteine residue in the extracellular domain of FGFR3 in thanatophoric dysplasia type I
[LiteratureReference:2064369] Fibroblast growth factor receptor 3 S249C mutation in virus associated squamous cell carcinomas
[LiteratureReference:2064373] FGFR3 mutations in prostate cancer: association with low-grade tumors
modified[InstanceEdit:1493888] Rothfels, K, 2011-08-16
[InstanceEdit:2023373] Rothfels, K, 2011-12-07
[InstanceEdit:2033290] Rothfels, K, 2012-01-09
[InstanceEdit:2064384] Rothfels, K, 2012-01-18
[InstanceEdit:3450990] Jupe, S, 2013-05-16
[InstanceEdit:5649572] Rothfels, Karen, 2014-11-20
nameFGFR3b S249C
Fibroblast growth factor receptor 3b S249C
FGR3_HUMAN S249C
FGFR3-2 S249C
referenceEntity[ReferenceIsoform:147316] UniProt:P22607-2 FGFR3 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2298503] R-HSA-1226109.1
startCoordinate23
(hasComponent)[Complex:1226110] FGFR3b S249C mutant dimer [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:2012043] FGFR3 cysteine mutants [plasma membrane] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9880985] Update Tracker - [EntityWithAccessionedSequence:1226109] FGFR3b S249C [plasma membrane] - v45:[addName]
[_UpdateTracker:9891466] Update Tracker - [EntityWithAccessionedSequence:1226109] FGFR3b S249C [plasma membrane] - v52:[modifyName]
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No pathways have been reviewed or authored by FGFR3b S249C [plasma membrane] (1226109)