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Details on Person Peroxynitrite is reduced to nitrite by Tpx

Class:Id	Reaction:1222755
_displayName	Peroxynitrite is reduced to nitrite by Tpx
_doRelease	TRUE
_timestamp	2014-07-14 09:07:43
authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
catalystActivity	[CatalystActivity:1222606] peroxiredoxin activity of Tpx dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1222482] Jassal, B, 2011-02-28
disease	[Disease:1660556] tuberculosis
edited	[InstanceEdit:1222482] Jassal, B, 2011-02-28
input	[SimpleEntity:1222481] Peroxynitrite [cytosol] [SimpleEntity:1222481] Peroxynitrite [cytosol] [EntityWithAccessionedSequence:1222392] Tpx [cytosol] [Mycobacterium tuberculosis] [EntityWithAccessionedSequence:1222392] Tpx [cytosol] [Mycobacterium tuberculosis]
isChimeric	FALSE
literatureReference	[LiteratureReference:1222378] Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis [LiteratureReference:1222577] Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis
modified	[InstanceEdit:1475050] Jassal, B, 2011-08-08 [InstanceEdit:1641501] Jassal, B, 2011-10-11 [InstanceEdit:1963552] Jassal, B, 2011-11-03 [InstanceEdit:1996247] Matthews, L, 2011-11-18 [InstanceEdit:2105559] Jassal, B, 2012-02-10 [InstanceEdit:2143452] Jassal, Bijay, 2012-02-25 [InstanceEdit:2201373] Jassal, B, 2012-04-20 [InstanceEdit:2213260] Jassal, B, 2012-04-30 [InstanceEdit:3508881] Jassal, B, 2013-05-20 [InstanceEdit:5607580] Jassal, Bijay, 2014-07-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Peroxynitrite is reduced to nitrite by Tpx
output	[SimpleEntity:1222379] Nitrite [cytosol] [SimpleEntity:1222379] Nitrite [cytosol] [SimpleEntity:29356] H2O [cytosol] [EntityWithAccessionedSequence:1222496] Tpx(ox.) [cytosol] [Mycobacterium tuberculosis] [EntityWithAccessionedSequence:1222496] Tpx(ox.) [cytosol] [Mycobacterium tuberculosis] [SimpleEntity:29356] H2O [cytosol]
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
releaseDate	2012-06-12
reviewed	[InstanceEdit:2213261] Warner, D, 2012-04-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295300] R-HSA-1222755.2
summation	[Summation:1222336] Tpx, like AhpC, is a peroxiredoxin with alkylhydroperoxidase...
(hasEvent)	[Pathway:1222538] Tolerance by Mtb to nitric oxide produced by macrophages [Homo sapiens]
(precedingEvent)	[Reaction:1222644] TrxA/B1 reactivates Tpx [Homo sapiens] [Reaction:1222740] TrxB1 reactivates Tpx [Mycobacterium tuberculosis]
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No pathways have been reviewed or authored by Peroxynitrite is reduced to nitrite by Tpx (1222755)