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Details on Person Ogt-mediated DNA Damage Reversal

Class:Id	Reaction:1222355
_displayName	Ogt-mediated DNA Damage Reversal
_doRelease	FALSE
_timestamp	2016-07-15 23:49:36
authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
catalystActivity	[CatalystActivity:1222572] methylated-DNA-[protein]-cysteine S-methyltransferase activity of Ogt [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1222482] Jassal, B, 2011-02-28
edited	[InstanceEdit:165073] Joshi-Tope, G, 0000-00-00 00:00:00
goBiologicalProcess	[GO_BiologicalProcess:17672] DNA alkylation repair
inferredFrom	[Reaction:1222504] Ogt-mediated DNA Damage Reversal [Escherichia coli]
input	[OtherEntity:109735] 6-O-methyguanine containing damaged DNA [nucleoplasm] [EntityWithAccessionedSequence:1222381] Ogt [nucleoplasm] [Mycobacterium tuberculosis]
literatureReference	[LiteratureReference:2201206] The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
modified	[InstanceEdit:1470059] Jassal, Bijay, 2011-08-02 [InstanceEdit:1963552] Jassal, B, 2011-11-03 [InstanceEdit:1996247] Matthews, L, 2011-11-18 [InstanceEdit:2105559] Jassal, B, 2012-02-10 [InstanceEdit:2201272] Jassal, B, 2012-04-19 [InstanceEdit:2201373] Jassal, B, 2012-04-20 [InstanceEdit:5255454] D'Eustachio, Peter, 2014-02-06 [InstanceEdit:5607580] Jassal, Bijay, 2014-07-14 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	Ogt-mediated DNA Damage Reversal
output	[OtherEntity:109736] DNA with no 6-O-methylated guanine [nucleoplasm] [EntityWithAccessionedSequence:1222659] Ogt(S-methyl-cysteine) [nucleoplasm] [Mycobacterium tuberculosis]
relatedSpecies	[Species:176806] Mycobacterium tuberculosis
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8899124] R-HSA-1222355.1
summation	[Summation:109760] MGMT, just like its E.coli homolog Ada, is an O-6-methylguan...
(hasEvent)	[Pathway:1500751] DNA repair [Homo sapiens]
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No pathways have been reviewed or authored by Ogt-mediated DNA Damage Reversal (1222355)