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Details on Person Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs [plasma membrane]

Class:Id	Complex:1220579
_displayName	Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs [plasma membrane]
_timestamp	2012-04-27 18:34:19
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1220584] Orlic-Milacic, Marija, 2011-02-22
disease	[Disease:1500689] cancer
hasComponent	[DefinedSet:1216522] Covalent EGFR tyrosine kinase inhibitors [cytosol] [DefinedSet:1216522] Covalent EGFR tyrosine kinase inhibitors [cytosol] [DefinedSet:1220585] Resistant ligand-responsive EGFR mutants [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:1225849] Orlic-Milacic, Marija, 2011-03-02 [InstanceEdit:1247347] Orlic-Milacic, Marija, 2011-04-01 [InstanceEdit:1500923] Orlic-Milacic, Marija, 2011-08-22 [InstanceEdit:1667318] Orlic-Milacic, Marija, 2011-10-14 [InstanceEdit:1667625] Orlic-Milacic, Marija, 2011-10-14 [InstanceEdit:1667632] Orlic-Milacic, Marija, 2011-10-14 [InstanceEdit:1996378] Orlic-Milacic, Marija, 2011-11-19 [InstanceEdit:2213009] Matthews, L, 2012-04-27
name	Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2018294] R-HSA-1220579.1
(output)	[Reaction:1220611] Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9872610] Update Tracker - [Complex:1220579] Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs [plasma membrane] - v41:[removeCompartment, updateContainedComponent] [_UpdateTracker:9873262] Update Tracker - [Complex:1220579] Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs [plasma membrane] - v42:[updateContainedComponent]
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No pathways have been reviewed or authored by Resistant ligand-responsive EGFR mutants:Covalent EGFR TKIs [plasma membrane] (1220579)