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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person EGFRvIII [plasma membrane]

Class:IdEntityWithAccessionedSequence:1214162
_displayNameEGFRvIII [plasma membrane]
_timestamp2013-06-06 16:42:21
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1214163] Orlic-Milacic, Marija, 2011-02-11
crossReference[DatabaseIdentifier:1996305] COSMIC:COSM21351
disease[Disease:1247632] glioblastoma
[Disease:1996318] astrocytoma
[Disease:1996312] brain glioma
[Disease:1500689] cancer
[Disease:1981182] lung squamous cell carcinoma
endCoordinate1210
hasModifiedResidue[FragmentDeletionModification:1246108] Deletion of residues 30 to 296
[ReplacedResidue:1996332] L-arginine 297 replaced with glycine
modified[InstanceEdit:1225864] Orlic-Milacic, Marija, 2011-03-02
[InstanceEdit:1246128] Orlic-Milacic, Marija, 2011-04-01
[InstanceEdit:1247634] Orlic-Milacic, Marija, 2011-04-04
[InstanceEdit:1248015] Orlic-Milacic, Marija, 2011-04-08
[InstanceEdit:1248671] Orlic-Milacic, Marija, 2011-04-11
[InstanceEdit:1500859] Orlic-Milacic, Marija, 2011-08-22
[InstanceEdit:1996363] Orlic-Milacic, Marija, 2011-11-19
[InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
nameEGFRvIII
EGFR V30_R297delinsG mutant
Epidermal Growth Factor Receptor V30_R297delinsG mutant
EGFR Val30_Arg297delinsGly mutant
referenceEntity[ReferenceGeneProduct:54208] UniProt:P00533 EGFR [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2017457] R-HSA-1214162.1
startCoordinate25
summation[Summation:1214165] EGFR V30_R297delinsG mutant of EGFR, commonly known as EGFRv...
(diseaseEntity)[EntityFunctionalStatus:9630152] gain_of_function of EGFRvIII [plasma membrane]
(hasComponent)[Complex:1248004] EGFRvIII mutant:HSP90:CDC37 [plasma membrane] [Homo sapiens]
(input)[Reaction:1247999] EGFRvIII mutant binds chaperone proteins HSP90 and CDC37 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9887720] Update Tracker - [EntityWithAccessionedSequence:1214162] EGFRvIII [plasma membrane] - v46:[modifyName]
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No pathways have been reviewed or authored by EGFRvIII [plasma membrane] (1214162)