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Details on Person Jupe, S, 2011-02-11
| Class:Id | InstanceEdit:1213499 |
| _displayName | Jupe, S, 2011-02-11 |
| _timestamp | 2011-02-11 13:20:26 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2011-02-11 18:19:14 |
| (created) | [Person:1213496] Osawa, M [LiteratureReference:1213497] Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID) [Person:1213498] Frattini, A [Person:1213500] Macchi, P [LiteratureReference:1213501] Activation of the interleukin 2 receptor: a possible role for tyrosine phosphatases [Person:1213502] Roberts, JL [Person:1213503] Shirasawa, T [LiteratureReference:1213504] Developmental defects of lymphoid cells in Jak3 kinase-deficient mice [Person:1213505] Buckley, RH [Person:1213506] Kempshall, SJ |
| (modified) | [Summation:451919] Receptor activation involves JAK1 and JAK3 as T-cells from m... [Reaction:452091] Phosphorylation of IL2RB Y338 enables SHC recruitment [Homo sapiens] [Reaction:452097] Recruited STAT5 is phosphorylated [Homo sapiens] [Reaction:452100] SHC1 bound to IL2 receptor is phosphorylated [Homo sapiens] [Reaction:452108] Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment [Homo sapiens] [Summation:452115] STAT5 alpha and beta are recruited to the receptor complex a... [Summation:453109] Phosphorylation of IL2RB Y338 creates a binding site for the... [BlackBoxEvent:507937] STAT5 dimers translocate to the nucleus [Homo sapiens] [Summation:507992] Interleukin-7 (IL7)-activated Signal transducer and activato... [BlackBoxEvent:508451] PTK2B is phosphorylated [Homo sapiens] |
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No pathways have been reviewed or authored by Jupe, S, 2011-02-11 (1213499)