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Details on Person Jupe, S, 2011-02-11
| Class:Id | InstanceEdit:1213487 |
| _displayName | Jupe, S, 2011-02-11 |
| _timestamp | 2011-02-11 13:15:52 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2011-02-11 18:15:34 |
| (created) | [LiteratureReference:1213486] Signaling domains of the interleukin 2 receptor [LiteratureReference:1213488] The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals [LiteratureReference:1213489] Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation [Person:1213490] Greenberg, PD [Summation:1213491] Cytokine receptor common gamma subunit (IL2RG, IL-2 receptor... [InstanceEdit:1213492] Villarino, A, 2011-02-11 [Person:1213493] Kimmel, L [Person:1213494] Villarino, Alejandro [Person:1213495] Hymel, A |
| (modified) | [Reaction:450027] Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta [Homo sapiens] [Reaction:450054] Interleukin-2 receptor alpha binds interleukin-2 [Homo sapiens] [Reaction:450063] Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit [Homo sapiens] [Reaction:451895] IL2RG binds JAK3 [Homo sapiens] [Summation:451896] Janus Kinase 1 (JAK1) constitutively associates with IL-2R b... [Reaction:451900] IL2RB binds JAK1 [Homo sapiens] [Pathway:451927] Interleukin-2 family signaling [Homo sapiens] [Summation:452111] Mutation analysis has shown that Y338, Y392 and Y510 are inv... [Reaction:452122] JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB [Homo sapiens] [Summation:507806] Following stimulation by IL2, the IL2R beta chain become pho... |
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No pathways have been reviewed or authored by Jupe, S, 2011-02-11 (1213487)