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Details on Person KMT2A [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:1183223
_displayName	KMT2A [nucleoplasm]
_timestamp	2014-11-20 03:24:40
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1183217] Jassal, B, 2011-02-10
endCoordinate	3969
modified	[InstanceEdit:3239028] Jupe, S, 2013-03-27 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:5244704] Jupe, S, 2014-01-20
name	KMT2A MLL1 Histone-lysine N-methyltransferase MLL MLL MLL1_HUMAN
referenceEntity	[ReferenceGeneProduct:56674] UniProt:Q03164 KMT2A [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5646353] R-HSA-1183223.1
startCoordinate	1
(activeUnit)	[CatalystActivity:8865499] histone H3K4 methyltransferase activity of RUNX1:CBFB:KMT2A:SPI1 gene:Nucleosome [nucleoplasm] [CatalystActivity:8865521] histone H3K4 methyltransferase activity of RUNX1:Cbfb:KMT2A:Spi1 gene:Nucleosome [nucleoplasm] [CatalystActivity:9677011] histone H3K4 methyltransferase activity of HOXA2,(HOXA10) gene:nucleosome:MLL1 complex [nucleoplasm]
(hasComponent)	[Complex:8865480] RUNX1:CBFB:KMT2A [nucleoplasm] [Homo sapiens] [Complex:8865517] RUNX1:Cbfb:KMT2A [nucleoplasm] [Homo sapiens] [Complex:9677746] MLL1 complex (p-S49-WDR5) [nucleoplasm] [Homo sapiens] [Complex:9860206] SIRT1:p-S90-BMAL1:p-T451,T461,S440,S441,S446-CLOCK:Nucleosome with H3K9acK14ac and H4K16ac:PER2 gene [nucleoplasm] [Homo sapiens] [Complex:9860210] SIRT1:p-S90,Ac-K538-BMAL1:p-Y451,T461,S440,S441,S446-CLOCK:Nucleosome with H3K9acH3K14ac and H4K16ac:PER2 gene [nucleoplasm] [Homo sapiens] [Complex:9909389] p-S90-BMAL1:p-T451,T461-CLOCK:CREBBP:KMT2A:PER3 gene [nucleoplasm] [Homo sapiens] [Complex:9920693] p-S90-BMAL1:p-T451,T461,S440,S441,S446-CLOCK:CREBBP:KMT2A:PER3 gene [nucleoplasm] [Homo sapiens] [Complex:9920712] p-S90,Ac-K538-BMAL1:p-T451,T461,S440,S441,S446-CLOCK:CREBBP:KMT2A:PER3 gene [nucleoplasm] [Homo sapiens] [Complex:9922275] p-S90,Ac-K538-BMAL1:p-S,T451,T461,S440,S441,S446-CLOCK:CREBBP:KMT2A:PER3 gene [nucleoplasm] [Homo sapiens] [Complex:9922977] p-S90-BMAL1:p-T451,T461,S440,S441,S446-CLOCK:CREBBP:KMT2A:PER2 gene [nucleoplasm] [Homo sapiens] List all 36 refering instances
(hasMember)	[CandidateSet:1183246] Histone-lysine methyltransferases [nucleoplasm] [Homo sapiens] [CandidateSet:5244745] KMT2A-E, SETD1A,(SETD1B) [nucleoplasm] [Homo sapiens]
(input)	[Reaction:8865482] KMT2A (MLL) binds RUNX1 [Homo sapiens] [Reaction:9909400] p-S90-BMAL1:p-T451,T461-CLOCK and coactivators bind the PER3 gene [Homo sapiens] [Reaction:9922982] p-S90-BMAL1:p-T451,T461-CLOCK,p-NPAS2 and coactivators bind the PER1 gene [Homo sapiens] [Reaction:9922994] p-S90-BMAL1:p-T451,T461-CLOCK,p-NPAS2 and coactivators bind the CRY1 gene [Homo sapiens] [Reaction:9922998] p-S90-BMAL1:p-T451,T461-CLOCK,p-NPAS2 and coactivators bind the PER2 gene [Homo sapiens] [Reaction:9923010] p-S90-BMAL1:p-T451,T461-CLOCK and coactivators bind the NR1D1 (REV-ERBA) gene [Homo sapiens] [Reaction:9925650] p-S90-BMAL1:p-T451,T461-CLOCK and coactivators bind the CRY2 gene [Homo sapiens] [Reaction:9925862] p-S90-BMAL1:p-T451,T461-CLOCK and coactivators bind the RORC gene [Homo sapiens] [Reaction:9929319] p-90-BMAL1:p-T451,T461-CLOCK and coactivators bind the DBP gene [Homo sapiens]
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No pathways have been reviewed or authored by KMT2A [nucleoplasm] (1183223)