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Details on Person EGFR L747_A750del spanning mutants [plasma membrane]

Class:Id	CandidateSet:1182964
_displayName	EGFR L747_A750del spanning mutants [plasma membrane]
_timestamp	2016-07-15 23:49:25
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1182968] Orlic-Milacic, Marija, 2011-02-09
disease	[Disease:1500689] cancer
hasCandidate	[EntityWithAccessionedSequence:1228025] EGFR E746_S752delinsV [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228031] EGFR E746_T751delinsA [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228034] EGFR L747_A750delinsP [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228016] EGFR L747_S752del [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228015] EGFR L747_T751del [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228012] EGFR L747_T751delinsP [plasma membrane] [Homo sapiens]
hasMember	[EntityWithAccessionedSequence:1181211] EGFR E746_A750del [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228010] EGFR L747_P753delinsS [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:1181035] Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib [LiteratureReference:1181048] EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
modified	[InstanceEdit:1182974] Orlic-Milacic, Marija, 2011-02-09 [InstanceEdit:1182979] Orlic-Milacic, Marija, 2011-02-09 [InstanceEdit:1228045] Orlic-Milacic, Marija, 2011-03-16 [InstanceEdit:1247850] Orlic-Milacic, Marija, 2011-04-07 [InstanceEdit:1247851] Orlic-Milacic, Marija, 2011-04-07 [InstanceEdit:1667317] Orlic-Milacic, Marija, 2011-10-14 [InstanceEdit:1809163] Orlic-Milacic, Marija, 2011-10-24 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	EGFR L747_A750del spanning mutants
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8894493] R-HSA-1182964.1
summation	[Summation:1181238] Most EGFR exon 19 deletions found in NSCLCs span LREA amino ...
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No pathways have been reviewed or authored by EGFR L747_A750del spanning mutants [plasma membrane] (1182964)