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Details on Person Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
| Class:Id | LiteratureReference:1181035 |
| _displayName | Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib |
| _timestamp | 2011-01-27 17:34:07 |
| author | [Person:375194] Lynch, TJ [Person:390170] Bell, DW [Person:416553] Sordella, R [Person:1181033] Gurubhagavatula, S [Person:1181029] Okimoto, RA [Person:1181039] Brannigan, BW [Person:1181036] Harris, PL [Person:1181030] Haserlat, SM [Person:1181038] Supko, JG [Person:1181031] Haluska, FG [Person:1181032] Louis, DN [Person:1181034] Christiani, DC [Person:416598] Settleman, J [Person:390192] Haber, DA |
| created | [InstanceEdit:1181037] Orlic-Milacic, Marija, 2011-01-27 |
| journal | N Engl J Med |
| pages | 2129-39 |
| pubMedIdentifier | 15118073 |
| title | Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib |
| volume | 350 |
| year | 2004 |
| (literatureReference) | [EntityWithAccessionedSequence:1177542] EGFR L861Q [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1181211] EGFR E746_A750del [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1181399] EGFR E746_A750del;T790M [plasma membrane] [Homo sapiens] [CandidateSet:1182964] EGFR L747_A750del spanning mutants [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228010] EGFR L747_P753delinsS [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1228038] p-6Y-EGFR L747_P753delinsS [plasma membrane] [Homo sapiens] [Summation:1181055] L861Q, a substitution of leucine 861 with glutamine, is a do... [Summation:1181238] Most EGFR exon 19 deletions found in NSCLCs span LREA amino ... [Summation:1181246] Signaling by EGFR is frequently activated in cancer through ... [Pathway:1169434] Signaling by constitutively active EGFR kinase domain mutants [Homo sapiens] |
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No pathways have been reviewed or authored by Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib (1181035)