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Details on Person Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants
| Class:Id | LiteratureReference:1181018 |
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| _displayName | Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants |
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| _timestamp | 2011-01-26 20:05:45 |
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| author | [Person:1169426] Greulich, Heidi
[Person:1181022] Chen, TH
[Person:1181021] Feng, WL
[Person:1181013] Jänne, PA
[Person:1181009] Alvarez, JV
[Person:1181024] Zappaterra, M
[Person:1181008] Bulmer, SE
[Person:879895] Frank, DA
[Person:184060] Hahn, WC
[Person:188357] Sellers, WR
[Person:1169419] Meyerson, M |
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| created | [InstanceEdit:1181016] Orlic-Milacic, Marija, 2011-01-26 |
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| journal | PLoS Med |
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| pages | e313 |
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| pubMedIdentifier | 16187797 |
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| title | Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants |
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| volume | 2 |
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| year | 2005 |
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| (literatureReference) | [Summation:1173215] EGFR ligand-responsive mutants dimerize spontaneously, witho...
[Summation:1181246] Signaling by EGFR is frequently activated in cancer through ...
[Summation:1225942] SOS is the guanine nucleotide exchange factor (GEF) for Ras....
[Pathway:1169434] Signaling by constitutively active EGFR kinase domain mutants [Homo sapiens]
[Reaction:1220612] Binding of EGF to ligand-responsive EGFR mutants [Homo sapiens]
[Reaction:1220613] EGF-induced dimerization of ligand-responsive EGFR mutants [Homo sapiens]
[Reaction:1220614] Spontaneous dimerization of ligand-responsive EGFR mutants [Homo sapiens]
[Reaction:1225947] Binding of SHC1 to p-6Y-EGFR mutants [Homo sapiens]
[Reaction:1225949] Binding of CBL to ligand-responsive p-6Y-EGFR mutants [Homo sapiens]
[Reaction:1225950] Binding of GRB2:SOS1 complex to phosphorylated ligand-responsive EGFR mutants [Homo sapiens] |
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